Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 2/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | SRC | P12931 | 1/20 | 0.46 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.46 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.45 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.44 |
| ▸ | CPN1 | P15169 | 1/20 | 0.43 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27843751 | 0.98 | HRH1 (0.54) | HRH1CYP2C19EPHX1HTR2ACYP2D6 | |
| Hydrochloric Acid SCHEMBL1093394 | 0.98 | HRH1 (0.54) | HRH1CYP2C19EPHX1HTR2ACYP2D6 | |
| SCHEMBL3781893 | 0.88 | HRH1 (0.59) | HRH1CYP2C19EPHX1HTR2ACYP2D6 | |
| SCHEMBL11115550 | 0.88 | HRH1 (0.56) | HRH1CYP2C19EPHX1HTR2ACYP2D6 | |
| SCHEMBL30371912 | 0.87 | CYP2C19 (0.61) | CYP2C19EPHX1CYP2D6SRCLMNA | |
| SCHEMBL5322781 | 0.86 | HRH1 (0.52) | HRH1CYP2C19EPHX1HTR2ATBXAS1 | |
| SCHEMBL27691659 | 0.86 | EPHX1 (0.61) | HRH1CYP2C19EPHX1HTR2ACYP2D6 | |
| SCHEMBL11502865 | 0.86 | HRH1 (0.54) | HRH1CYP2C19EPHX1HTR2ACYP2D6 | |
| SCHEMBL20850639 | 0.85 | TBXAS1 (0.54) | HRH1CYP2C19EPHX1HTR2ATBXAS1 | |
| SCHEMBL12824732 | 0.84 | HRH1 (0.52) | HRH1CYP2C19EPHX1HTR2AGABBR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 149 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114432423-A | NF for treating diseases and disorderskInhibitors of B activity | 拉金德拉·萨哈伊·巴特纳格尔 | 2022-05-06 | — | — | CN | claimed |
| EP-3197474-A2 | INHIBITORS OF NF KAPPA-B ACTIVITY FOR TREATMENT OF DISEASES AND DISORDERS | Bhatnagar, Rajendra, Sahai (US) | 2017-08-02 | — | — | EP | claimed |
| WO-2016049580-A2 | INHIBITORS OF NF KAPPA-B ACTIVITY FOR TREATMENT OF DISEASES AND DISORDERS | BHATNAGAR RAJENDRA SAHAI (US) | 2016-03-31 | — | — | WO | claimed |
| CN-103547240-B | For the autonomic balance of the mankind and the system and method maintaining health | SOLACE LIFESCIENCES, INC. (US) | 2016-03-30 | — | — | CN | claimed |
| CN-103547240-A | Systems and methods for balancing and maintaining the health of the human autonomic nervous system | SOLACE LIFESCIENCES INC | 2014-01-29 | — | — | CN | claimed |
| CN-102282144-A | Oxadiazole derivatives as sphingosine-1-phosphate 1 receptor agonists | — | 2011-12-14 | — | — | CN | claimed |
| US-7309719-B1 | Storage stability; gabapentin and pregabalin, and neutral alpha -amino acid | WARNER LAMBERT COMPANY, LLC (US) | 2007-12-18 | — | — | US | claimed |
| CN-1303991-C | Stabilized pharmaceutical preparations of gamma-aminobutyric acid derivative process for preparing the same | WARNER LAMBERT CO (US) | 2007-03-14 | — | — | CN | claimed |
| EP-1174151-B1 | THERAPEUTIC TREATMENT OF EOSINOPHILIA USING CHYMASE INHIBITORS AS THE ACTIVE INGREDIENT | DAIICHI ASUBIO PHARMA CO LTD (JP) | 2007-01-24 | — | — | EP | claimed |
| CN-1206212-C | Tri-substd. phenyl derivs. and analogues | ASTRAZENECA AB (SE) | 2005-06-15 | — | — | CN | claimed |
| EP-1077692-B1 | AMINO ACID STABILIZED GABAPENTIN AND PREGABALIN PREPARATIONS AND PROCESS FOR PREPARING THE SAME | WARNER LAMBERT CO (US) | 2004-07-28 | — | — | EP | claimed |
| US-6677344-B2 | Chymase inhibitor for the treatment of eosinophilia | DAIICHI SUNTORY PHARMA CO., LTD. (JP) | 2004-01-13 | — | — | US | claimed |
| US-6500835-B2 | FOR PROPHYLAXIS AND THERAPY OF FIBROSIS INVOLVING EXTRACELLULAR MATRIX DYSBOLISM HAVING A CHYMASE INHIBITOR AS AN EFFECTIVE INGREDIENT; SIDE EFFECT REDUCTION | SUNTORY LIMITED (JP) | 2002-12-31 | — | — | US | claimed |
| CN-1301155-A | Stable pharmaceutical formulation of gamma-aminobutyric acid derivatives and process for preparing the same | WARNER LAMBERT CO (US) | 2001-06-27 | — | — | CN | claimed |
| WO-1996011680-A2 | USE OF GABA AGONISTS IN THE TREATMENT OF EMESIS | GLAXO GROUP LIMITED (GB) | 1996-04-25 | — | — | WO | claimed |
| EP-0025846-B1 | IMPROVED PROCESS FOR THE PREPARATION OF VINYLCYCLOPROPANE DERIVATIVES | NATIONAL DISTILLERS AND CHEMICAL CORPORATION (US) | 1984-03-07 | — | — | EP | claimed |
| US-20250302803-A1 | ARYL-SUBSTITUTED ACETAMIDE AND PYRROLIDIN-2-ONE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF SEIZURES | UNIVERSITY OF HOUSTON SYSTEM (US) | 2025-10-02 | — | — | US | disclosed |
| US-12357610-B2 | Aryl-substituted acetamide and pyrrolidin-2-one derivatives and their use for the treatment of seizures | UNIVERSITY OF HOUSTON SYSTEM (US) | 2025-07-15 | — | — | US | disclosed |
| US-4158733-A | 7β-Acyloxy-3-acetoxymethyl cephalosporins | SMITHKLINE CORPORATION (US) | 1979-06-19 | — | — | US | disclosed |
| US-4144232-A | Substituted azetidin-2-one antibiotics | ELI LILLY AND COMPANY (US) | 1979-03-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12357610-B2 | Aryl-substituted acetamide and pyrrolidin-2-one derivatives and their use for the treatment of seizures | AADAC, GABRB2, GABARAPL2 | HRH1 1750/4885CYP2C19 148/4885EPHX1 1151/4885 |
| US-20250302803-A1 | ARYL-SUBSTITUTED ACETAMIDE AND PYRROLIDIN-2-ONE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF SEIZURES | AADAC, GABRB2, GABARAPL2 | HRH1 1750/4885CYP2C19 148/4885EPHX1 1151/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.