SCHEMBL28464

SCHEMBL28464

NS(=O)(=O)c1cccc2ccccc12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 7/20 1.00
CA1 P00915 6/20 1.00
CA9 Q16790 5/20 1.00
CDK2 P24941 1/20 0.61
F2 P00734 3/20 0.56
PRSS1 P07477 3/20 0.56
PRSS2 P07478 3/20 0.56
PRSS3 P35030 3/20 0.56
HTR6 P50406 1/20 0.56
LDHA P00338 1/20 0.55
CA12 O43570 3/20 0.52
CA4 P22748 2/20 0.52
CA6 P23280 2/20 0.52
CYP2C9 P11712 2/20 0.52
CA5A P35218 1/20 0.52
CA7 P43166 1/20 0.52
CA14 Q9ULX7 1/20 0.52
CA5B Q9Y2D0 1/20 0.52
MEN1 O00255 1/20 0.50
KMT2A Q03164 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29529240 1.00 CA2 (1.00) CA2CA1CA9CDK2F2
Hydrochloric Acid SCHEMBL951327 0.98 CA2 (0.96) CA2CA1CA9CDK2F2
Benzene SCHEMBL11062753 0.98 CA2 (0.96) CA2CA1CA9CDK2F2
Hydrochloric Acid SCHEMBL8125684 0.96 CA2 (0.92) CA2CA1CA9CDK2F2
Phosphoric Acid SCHEMBL28841729 0.90 CA2 (0.81) CA2CA1CA9CDK2F2
Isothiocyanate SCHEMBL28619475 0.89 CA2 (0.79) CA2CA1CA9CDK2F2
Acetamide SCHEMBL28617889 0.89 CA2 (0.79) CA2CA1CA9CDK2F2
SCHEMBL3149642 0.88 CA2 (0.78) CA2CA1CA9CDK2F2
Pyrrolidine SCHEMBL17599458 0.86 CA1 (0.73) CA2CA1CA9CDK2F2
SCHEMBL9138970 0.85 CDK2 (0.78) CA2CA1CA9CDK2LDHA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3747 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4745119-A1 ISOCYANATE COMPOSITION Hanwha Solutions Corporation (KR) 2026-05-20 EP claimed
WO-2025042219-A1 ISOCYANATE COMPOSITION 한화솔루션 주식회사 2025-02-27 WO claimed
CN-119233829-A Pharmaceutical composition for preventing, inhibiting or treating symptoms associated with pseudoallergy 学校法人高崎健康福祉大学 2024-12-31 CN claimed
CN-118574812-A Benzenesulfonamide thiazole compounds and their use for the treatment of cancer 国家医疗保健研究所 2024-08-30 CN claimed
CN-118176003-A Medicaments comprising P2X4 receptor antagonists for the prevention or treatment of nociceptive pain and/or visceral pain 日本化学药品株式会社 2024-06-11 CN claimed
CN-118019551-A Preventive or therapeutic agent for respiratory diseases 日本化学药品株式会社 2024-05-10 CN claimed
CN-117085146-A Metal framework preparation method and application of metal framework in targeted activation of endoplasmic reticulum stress 湖北医药学院 2023-11-21 CN claimed
US-11773057-B2 Naphthalenesulfonamide compound, preparation method, and application CHINA PHARMACEUTICAL UNIVERSITY (CN) 2023-10-03 US claimed
CN-115160193-B Naphthalene sulfonamide micromolecule compound and application thereof 中国人民解放军海军军医大学 2023-09-15 CN claimed
WO-2023067170-A1 COMPOUNDS FOR THE TREATMENT OF MALARIA FUNDACIÓ INSTITUT DE BIOENGINYERIA DE CATALUNYA (ES) 2023-04-27 WO claimed
US-4406875-A Radiolabeled amine compounds and their use BYK-MALLINCKRODT CIL B.V. (NL) 1983-09-27 US claimed
EP-0082203-A1 USE OF CALMODULIN BINDING DRUGS IN UTERUS TO PREVENT PREGNANCY THE UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) 1983-06-29 EP claimed
WO-1983000086-A1 USE OF CALMODULIN BINDING DRUGS IN UTERUS TO PREVENT PREGNANCY UNIV GEORGIA RES FOUND (US) 1983-01-20 WO claimed
EP-0042357-A2 Azo dyes, their preparation and use CIBA-GEIGY AG (CH) 1981-12-23 EP claimed
US-4292238-A Alkylation of benzthiazole-azo-phenylamine dyestuffs BAYER AKTIENGESELLSCHAFT (DE) 1981-09-29 US claimed
WO-1980001685-A1 RADIOLABELED AMINE COMPOUNDS AND THEIR USE BYK MALLINCKRODT CIL BV (NL) 1980-08-21 WO claimed
US-4146541-A YELLOW SHADE ON POLYESTERS CIBA-GEIGY AG (CH) 1979-03-27 US claimed
US-4021428-A 4-Piperidino-5-oxo-2-pyrazolines FUJI PHOTO FILM CO., LTD. (JA) 1977-05-03 US claimed
US-3996208-A PENICILLINS CIBA-GEIGY CORPORATION (US) 1976-12-07 US claimed
US-3956339-A 4-Pyridinio-5-pyrazolone salts, process for their preparation and their use FUJI PHOTO FILM CO., LTD. (JA) 1976-05-11 US claimed