Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 6/20 | 0.37 |
| ▸ | FABP3 | P05413 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 2/20 | 0.35 |
| ▸ | TSPO | P30536 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6691723 | 0.91 | TSPO (0.44) | FABP4FABP3HTR6TSPO | |
| SCHEMBL6129588 | 0.90 | FABP4 (0.36) | FABP4FABP3OPRM1OPRK1KCNH2 | |
| SCHEMBL27845011 | 0.90 | FABP4 (0.37) | FABP4FABP3POLBHTR6TSPO | |
| SCHEMBL27844976 | 0.90 | FABP4 (0.39) | FABP4FABP3POLBOPRM1OPRK1 | |
| SCHEMBL29862385 | 0.88 | PLA2G2A (0.47) | — | |
| SCHEMBL818609 | 0.88 | PLA2G2A (0.47) | — | |
| SCHEMBL27594802 | 0.88 | FABP4 (0.36) | FABP4FABP3OPRM1OPRK1KCNH2 | |
| SCHEMBL8371555 | 0.86 | PLA2G2A (0.46) | — | |
| SCHEMBL8374848 | 0.86 | FABP4 (0.41) | FABP4FABP3HTR6 | |
| SCHEMBL27845033 | 0.85 | TSPO (0.45) | HTR6TSPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102271507-A | Secreted phospholipase A2(SPLA2) Inhibitor and niacin pharmaceutical composition and method for treating cardiovascular diseases and dyslipidemia | — | 2011-12-07 | — | — | CN | disclosed |