Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MGAM | O43451 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ECE1 | P42892 | 1/20 | 0.34 |
| ▸ | MYC | P01106 | 1/20 | 0.34 |
| ▸ | MAX | P61244 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1923229 | 0.76 | BACE1 (0.37) | TDP1ALDH1A1MAPT | |
| SCHEMBL30370409 | 0.75 | MAPT (0.37) | KDM4EALDH1A1MAPTHTTKMT2A | |
| SCHEMBL18979820 | 0.75 | MAPT (0.37) | KDM4EALDH1A1MAPTHTTKMT2A | |
| SCHEMBL187794 | 0.75 | KDM4E (0.58) | KDM4ETDP1ALOX15ALDH1A1MAPT | |
| SCHEMBL3629670 | 0.72 | KDM4E (0.50) | KDM4ETDP1ALOX15TSHRACMSD | |
| SCHEMBL10025751 | 0.72 | NPC1 (0.51) | ALDH1A1MAPTKMT2AMEN1LMNA | |
| SCHEMBL3648082 | 0.71 | KDM4E (0.48) | KDM4ETDP1ALOX15TSHRACMSD | |
| SCHEMBL15898801 | 0.71 | KDM4E (0.48) | KDM4ETDP1ALOX15TSHRACMSD | |
| SCHEMBL16931203 | 0.70 | CASP6 (0.47) | KDM4ETDP1ALOX15TSHRACMSD | |
| SCHEMBL30194732 | 0.69 | KDM4E (0.48) | KDM4ETDP1ALOX15TSHRACMSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102197036-A | Novel benzofurans suitable as precursors to compounds for imaging amyloid deposits | ASTRAZENECA AB | 2011-09-21 | — | — | CN | disclosed |