Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.37 |
| ▸ | NQO2 | P16083 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | TYMS | P04818 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30370409 | 1.00 | MAPT (0.37) | MAPTNQO2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL5149307 | 0.81 | MAPT (0.34) | MAPTNQO2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28029112 | 0.81 | ALDH1A1 (0.37) | MAPTALDH1A1KMT2AMEN1CYP2D6 | |
| SCHEMBL1923229 | 0.79 | BACE1 (0.37) | MAPTNQO2ALDH1A1TYMSCYP2D6 | |
| SCHEMBL10309700 | 0.79 | MAPT (0.40) | MAPTNPC1RAB9ASMN1; SMN2S1PR4 | |
| SCHEMBL10025751 | 0.79 | NPC1 (0.51) | MAPTNPC1RAB9ASMN1; SMN2S1PR4 | |
| SCHEMBL1922830 | 0.79 | TDP1 (0.41) | MAPTALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL1809848 | 0.79 | SMN1; SMN2 (0.37) | MAPTNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL30152695 | 0.79 | SMN1; SMN2 (0.37) | MAPTNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL2986307 | 0.75 | MAPT (0.46) | MAPTNPC1RAB9ASMN1; SMN2S1PR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108689942-B | Nitrogen-containing bicyclic compound, and preparation method and application thereof | 广东东阳光药业有限公司 | 2023-06-09 | — | — | CN | disclosed |
| CN-116063240-A | Organic electroluminescent multi-host material, luminescent device and application | 宁波卢米蓝新材料有限公司 | 2023-05-05 | — | — | CN | disclosed |
| US-20170179407-A1 | CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME | SAMSUNG DISPLAY CO., LTD. (KR) | 2017-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170179407-A1 | CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME | CRY1, CRY2, CCNT1 | MAPT 1824/4885NQO2 1713/4885NPC1 1611/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.