SCHEMBL2784604

SCHEMBL2784604

CC(=O)N(c1ccccc1)c1ccc2oc3ccccc3c2c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 2/20 0.46
▸ NPC1 O15118 2/20 0.44
▸ RAB9A P51151 2/20 0.44
▸ BCAT1 P54687 2/20 0.43
▸ MEN1 O00255 2/20 0.42
▸ KMT2A Q03164 2/20 0.42
▸ KDM4E B2RXH2 2/20 0.42
▸ MAPT P10636 2/20 0.42
▸ HPGD P15428 2/20 0.42
▸ ALDH1A1 P00352 1/20 0.42
▸ SMN1; SMN2 Q16637 1/20 0.42
▸ TTR P02766 1/20 0.42
▸ MMP12 P39900 2/20 0.41
▸ MMP13 P45452 2/20 0.41
▸ TSHR P16473 2/20 0.41
▸ NPY5R Q15761 1/20 0.41
▸ KEAP1 Q14145 1/20 0.41
▸ HSP90AA1 P07900 1/20 0.41
▸ HSP90AB1 P08238 1/20 0.41
▸ GLA P06280 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2785057 0.95 NPC1 (0.48) LMNANPC1RAB9ABCAT1MEN1
SCHEMBL14295755 0.85 MMP12 (0.44) LMNANPC1RAB9AMEN1KMT2A
SCHEMBL14295751 0.82 MAOB (0.44) LMNANPC1RAB9ABCAT1MEN1
SCHEMBL8044893 0.77 NPSR1 (0.61) LMNANPC1RAB9AMEN1KMT2A
SCHEMBL15747045 0.76 MAPT (0.49) LMNANPC1RAB9AMEN1KMT2A
SCHEMBL23308823 0.76 MAPT (0.52) LMNANPC1RAB9ABCAT1MEN1
SCHEMBL10042889 0.76 MAPT (0.52) LMNANPC1RAB9ABCAT1MEN1
SCHEMBL14295296 0.76 MAPT (0.52) LMNANPC1RAB9ABCAT1MEN1
SCHEMBL15730657 0.76 MAPT (0.52) LMNANPC1RAB9ABCAT1MEN1
SCHEMBL12936127 0.76 MAPT (0.52) LMNANPC1RAB9ABCAT1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210384446-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2021-12-09 — — US disclosed
US-11133478-B2 Aromatic amine derivative and organic electroluminescent device using the same IDEMITSU KOSAN CO., LTD. (JP) 2021-09-28 — — US disclosed
US-20190221753-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2019-07-18 — — US disclosed
US-10297765-B2 Aromatic amine derivative and organic electroluminescent device using the same IDEMITSU KOSAN CO., LTD. (JP) 2019-05-21 — — US disclosed
US-20160285012-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2016-09-29 — — US disclosed
US-9391279-B2 Aromatic amine derivative and organic electroluminescent device using the same IDEMITSU KOSAN CO., LTD. (JP) 2016-07-12 — — US disclosed
EP-2239259-B1 AROMATIC AMINE DERIVATIVE AND USE OF THE SAME IN AN ORGANIC ELECTROLUMINESCENT DEVICE IDEMITSU KOSAN CO (JP) 2016-04-13 — — EP disclosed
US-20130253183-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2013-09-26 — — US disclosed
US-8518560-B2 Aromatic amine derivative and organic electroluminescent device using the same IDEMITSU KOSAN CO., LTD. (JP) 2013-08-27 — — US disclosed
US-20100314615-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2010-12-16 — — US disclosed
EP-2239259-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME Idemitsu Kosan Co., Ltd. (JP) 2010-10-13 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100314615-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME DDT, TYR, DDC LMNA 2810/4885NPC1 4655/4885RAB9A 3940/4885
US-20160285012-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME DDT, TYR, DDC LMNA 2810/4885NPC1 4655/4885RAB9A 3940/4885
US-20210384446-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME DDT, TYR, DDC LMNA 2810/4885NPC1 4655/4885RAB9A 3940/4885
US-11133478-B2 Aromatic amine derivative and organic electroluminescent device using the same DDT, TYR, DDC LMNA 2810/4885NPC1 4655/4885RAB9A 3940/4885
US-10297765-B2 Aromatic amine derivative and organic electroluminescent device using the same DDT, TYR, DDC LMNA 2810/4885NPC1 4655/4885RAB9A 3940/4885
US-20190221753-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME DDT, TYR, DDC LMNA 2810/4885NPC1 4655/4885RAB9A 3940/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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