Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.43 |
| ▸ | BCAT1 | P54687 | 3/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | AHR | P35869 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 2/20 | 0.42 |
| ▸ | TTR | P02766 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MMP12 | P39900 | 2/20 | 0.41 |
| ▸ | MMP13 | P45452 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2784604 | 0.95 | LMNA (0.46) | NPC1RAB9AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL14295751 | 0.86 | MAOB (0.44) | NPC1RAB9AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL14295755 | 0.83 | MMP12 (0.44) | NPC1RAB9AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL14295753 | 0.78 | NPC1 (0.40) | NPC1RAB9AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6494373 | 0.78 | MAPT (0.53) | NPC1RAB9AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6372659 | 0.77 | MAPT (0.57) | NPC1RAB9AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL22857677 | 0.75 | MAPT (0.50) | NPC1RAB9AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL1283826 | 0.75 | NPC1 (0.79) | NPC1RAB9AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL30765635 | 0.75 | NPC1 (0.79) | NPC1RAB9AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11887568 | 0.74 | ALOX5 (0.53) | MEN1KMT2AHSP90AA1HSP90AB1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4426679-A1 | SPIRO-(INDANE-FLUORENE) TYPE COMPOUNDS AND THEIR USE IN ORGANIC ELECTRONICS | DOTTIKON ES HOLDING AG (CH) | 2024-09-11 | — | — | EP | disclosed |
| WO-2023078824-A1 | SPIRO-(INDANE-FLUORENE) TYPE COMPOUNDS AND THEIR USE IN ORGANIC ELECTRONICS | DOTTIKON ES HOLDING AG (CH) | 2023-05-11 | — | — | WO | disclosed |
| US-20210384446-A1 | AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME | IDEMITSU KOSAN CO., LTD. (JP) | 2021-12-09 | — | — | US | disclosed |
| US-11133478-B2 | Aromatic amine derivative and organic electroluminescent device using the same | IDEMITSU KOSAN CO., LTD. (JP) | 2021-09-28 | — | — | US | disclosed |
| US-20190221753-A1 | AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME | IDEMITSU KOSAN CO., LTD. (JP) | 2019-07-18 | — | — | US | disclosed |
| US-10297765-B2 | Aromatic amine derivative and organic electroluminescent device using the same | IDEMITSU KOSAN CO., LTD. (JP) | 2019-05-21 | — | — | US | disclosed |
| US-20160285012-A1 | AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME | IDEMITSU KOSAN CO., LTD. (JP) | 2016-09-29 | — | — | US | disclosed |
| US-9391279-B2 | Aromatic amine derivative and organic electroluminescent device using the same | IDEMITSU KOSAN CO., LTD. (JP) | 2016-07-12 | — | — | US | disclosed |
| EP-2239259-B1 | AROMATIC AMINE DERIVATIVE AND USE OF THE SAME IN AN ORGANIC ELECTROLUMINESCENT DEVICE | IDEMITSU KOSAN CO (JP) | 2016-04-13 | — | — | EP | disclosed |
| US-20130253183-A1 | AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME | IDEMITSU KOSAN CO., LTD. (JP) | 2013-09-26 | — | — | US | disclosed |
| US-8518560-B2 | Aromatic amine derivative and organic electroluminescent device using the same | IDEMITSU KOSAN CO., LTD. (JP) | 2013-08-27 | — | — | US | disclosed |
| US-20100314615-A1 | AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME | IDEMITSU KOSAN CO., LTD. (JP) | 2010-12-16 | — | — | US | disclosed |
| EP-2239259-A1 | AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME | Idemitsu Kosan Co., Ltd. (JP) | 2010-10-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100314615-A1 | AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME | DDT, TYR, DDC | NPC1 4655/4885RAB9A 3940/4885MEN1 2221/4885 |
| US-20160285012-A1 | AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME | DDT, TYR, DDC | NPC1 4655/4885RAB9A 3940/4885MEN1 2221/4885 |
| US-20210384446-A1 | AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME | DDT, TYR, DDC | NPC1 4655/4885RAB9A 3940/4885MEN1 2221/4885 |
| US-11133478-B2 | Aromatic amine derivative and organic electroluminescent device using the same | DDT, TYR, DDC | NPC1 4655/4885RAB9A 3940/4885MEN1 2221/4885 |
| US-10297765-B2 | Aromatic amine derivative and organic electroluminescent device using the same | DDT, TYR, DDC | NPC1 4655/4885RAB9A 3940/4885MEN1 2221/4885 |
| US-20190221753-A1 | AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME | DDT, TYR, DDC | NPC1 4655/4885RAB9A 3940/4885MEN1 2221/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.