SCHEMBL13950273

SCHEMBL13950273

CNC(CCCNC(=N)N)C(=O)OCOC(=O)C(CCCNC(=N)N)NC(=O)CC(C)=O

nearest known ligand 0.35

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ NPY4R P50391 13/20 0.35
▸ NPY1R P25929 8/20 0.35
▸ NPY5R Q15761 8/20 0.35
▸ NPY2R P49146 5/20 0.35
▸ L3MBTL1 Q9Y468 1/20 0.33
▸ C3AR1 Q16581 1/20 0.32
▸ KMT2A Q03164 2/20 0.32
▸ POLB P06746 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16659348 0.92 NMT2 (0.36) NPY4RNPY1RNPY5RNPY2RKMT2A
SCHEMBL16659354 0.88 NPY4R (0.33) NPY4RNPY1RNPY5RNPY2R
SCHEMBL27846680 0.86 NPY4R (0.42) NPY4RNPY1RNPY5RNPY2RC3AR1
SCHEMBL8737919 0.81 L3MBTL1 (0.31) L3MBTL1
SCHEMBL8019370 0.79 CAD (0.39) NPY4RNPY1RNPY5RNPY2RL3MBTL1
SCHEMBL27554606 0.79 CAD (0.39) NPY4RNPY1RNPY5RNPY2RL3MBTL1
SCHEMBL23048407 0.79 NPY4R (0.43) NPY4RNPY1RNPY5RNPY2RKMT2A
SCHEMBL13949746 0.79 NPY4R (0.43) NPY4RNPY1RNPY5RNPY2RKMT2A
SCHEMBL8005035 0.79 NPY4R (0.43) NPY4RNPY1RNPY5RNPY2RKMT2A
SCHEMBL160845 0.78 ALOX15 (0.36) NPY4RNPY1RNPY5RNPY2RKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090029937-A1 BIODEGRADABLE CATIONIC POLYMER GENE TRANSFER COMPOSITIONS AND METHODS OF USE CORNELL UNIVERSITY (US) 2009-01-29 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090029937-A1 BIODEGRADABLE CATIONIC POLYMER GENE TRANSFER COMPOSITIONS AND METHODS OF USE PEF1, PARG, PARN NPY4R 4214/4885NPY1R 3391/4885NPY5R 3972/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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