Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.37 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23780525 | 0.98 | MAPK1 (0.50) | SLC18A3MAPK1MAOAMAOBUSP30 | |
| SCHEMBL3535701 | 0.85 | MAOA (0.54) | SLC18A3MAPK1MAOAMAOBMAPT | |
| SCHEMBL8284787 | 0.85 | MAOA (0.54) | SLC18A3MAPK1MAOAMAOBMAPT | |
| SCHEMBL18951233 | 0.84 | MBTD1 (0.49) | SLC18A3MAPK1MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL7075696 | 0.83 | MAOA (0.60) | SLC18A3MAPK1MAOAMAOBMAPT | |
| Methyl Alcohol SCHEMBL27841069 | 0.82 | SLC18A3 (0.53) | SLC18A3MAPK1MAOAMAOBMAPT | |
| SCHEMBL29331244 | 0.80 | MAPT (0.47) | MAPK1MAOAMAOBMAPTHRH3 | |
| SCHEMBL17767835 | 0.79 | SLC18A3 (0.43) | SLC18A3MAPK1MAOAMAOBUSP30 | |
| Bicarbonate SCHEMBL5078500 | 0.77 | MAOA (0.55) | SLC18A3MAPK1MAOAMAOBMAPT | |
| SCHEMBL1028679 | 0.77 | SLC18A3 (0.34) | SLC18A3MAPK1MAOAMAOBUSP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104177349-A | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION LLC | 2014-12-03 | — | — | CN | disclosed |
| CN-101910161-A | Insecticidal compounds | SYNGENTA PARTICIPATIONS AG | 2010-12-08 | — | — | CN | disclosed |