Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.53 |
| ▸ | MAOA | P21397 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.48 |
| ▸ | AR | P10275 | 2/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.43 |
| ▸ | SMARCA2 | P51531 | 2/20 | 0.43 |
| ▸ | SMARCA4 | P51532 | 2/20 | 0.43 |
| ▸ | PBRM1 | Q86U86 | 2/20 | 0.43 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8284787 | 0.96 | MAOA (0.54) | SLC18A3MAOAMAOBMAPK1PDK2 | |
| SCHEMBL3535701 | 0.96 | MAOA (0.54) | SLC18A3MAOAMAOBMAPK1PDK2 | |
| SCHEMBL7075696 | 0.90 | MAOA (0.60) | SLC18A3MAOAMAOBMAPK1PDK2 | |
| Bicarbonate SCHEMBL5078500 | 0.87 | MAOA (0.55) | SLC18A3MAOAMAOBMAPK1PDK2 | |
| Acetic Acid SCHEMBL28984290 | 0.86 | MAOA (0.53) | SLC18A3MAOAMAOBMAPK1BCHE | |
| SCHEMBL23780525 | 0.84 | MAPK1 (0.50) | SLC18A3MAOAMAOBMAPK1ACHE | |
| SCHEMBL13695443 | 0.82 | MAOA (0.47) | SLC18A3MAOAMAOBMAPK1PDK2 | |
| Ammonia Solution, Strong SCHEMBL27847005 | 0.82 | SLC18A3 (0.49) | SLC18A3MAOAMAOBMAPK1ACHE | |
| SCHEMBL6446086 | 0.81 | MAOA (0.49) | SLC18A3MAOAMAOBMAPK1PDK2 | |
| SCHEMBL27865371 | 0.79 | OPRM1 (0.49) | PDK2NR1I2SMARCA2SMARCA4PBRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102216302-B | Akt and p70 s6 kinase inhibitors | LILLY CO ELI | 2013-08-21 | — | — | CN | disclosed |
| CN-102216302-A | Akt and p70 s6 kinase inhibitors | LILLY CO ELI | 2011-10-12 | — | — | CN | disclosed |