Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | XBP1 | P17861 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA7 | P43166 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28839013 | 0.87 | LMNA (0.49) | LMNAALDH1A1MAPTTSHRSMN1; SMN2 | |
| SCHEMBL11340951 | 0.75 | TSHR (0.62) | LMNAALDH1A1MAPTTSHRSMN1; SMN2 | |
| SCHEMBL21751904 | 0.74 | CA12 (0.39) | ALDH1A1S1PR3CA12CA1CA9 | |
| SCHEMBL10180637 | 0.73 | CA2 (0.58) | LMNAALDH1A1MAPTTSHRSMN1; SMN2 | |
| SCHEMBL4501364 | 0.71 | RAB9A (0.46) | LMNAALDH1A1MAPTTSHRHTT | |
| SCHEMBL11338130 | 0.71 | TSHR (0.57) | LMNAALDH1A1MAPTTSHRSMN1; SMN2 | |
| SCHEMBL27847781 | 0.71 | HTR2A (0.37) | ALDH1A1SMN1; SMN2NPC1MAPK1RAB9A | |
| SCHEMBL11340502 | 0.69 | LMNA (0.63) | LMNAALDH1A1MAPTTSHRSMN1; SMN2 | |
| SCHEMBL30084592 | 0.66 | ALDH1A1 (0.59) | LMNAALDH1A1MAPTTSHRSMN1; SMN2 | |
| SCHEMBL146202 | 0.66 | FLT3 (0.40) | LMNAALDH1A1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115057801-A | F-18 labeled PSMA (patterned Markov chain) targeted PET (polyethylene terephthalate) probe and preparation method thereof | 西南医科大学附属医院 | 2022-09-16 | — | — | CN | disclosed |