Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27848280 | 0.80 | ALDH1A1 (0.43) | ALDH1A1KDM4EMAPTMAPK1LMNA | |
| SCHEMBL19446710 | 0.79 | HRH4 (0.51) | ALDH1A1KDM4EHPGDTSHRHRH4 | |
| Hydrochloric Acid SCHEMBL27909753 | 0.79 | ALDH1A1 (0.42) | ALDH1A1KDM4EMAPTMAPK1LMNA | |
| SCHEMBL12240392 | 0.77 | SMN1; SMN2 (0.46) | ALDH1A1KDM4EMAPTMAPK1L3MBTL1 | |
| SCHEMBL14735613 | 0.75 | KMT2A (0.38) | ALDH1A1KDM4EMAPK1TSHRMEN1 | |
| SCHEMBL2366023 | 0.75 | HRH4 (0.46) | TSHRHRH4CYP1A2 | |
| Hydrochloric Acid SCHEMBL2366308 | 0.74 | HRH4 (0.45) | TSHRHRH4CYP1A2 | |
| SCHEMBL12292850 | 0.73 | HCRTR1 (0.38) | ALDH1A1KDM4EMAPTMAPK1L3MBTL1 | |
| SCHEMBL27829786 | 0.73 | OPRK1 (0.37) | ALDH1A1KDM4EMAPTMAPK1L3MBTL1 | |
| SCHEMBL27892721 | 0.72 | ALDH1A1 (0.51) | ALDH1A1KDM4EMAPTMAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102239152-B | Novel amide derivative and use thereof as medicine | MITSUBISHI TANABE PHARMA CORP. (JP) | 2014-10-29 | — | — | CN | disclosed |
| CN-102971291-A | Novel amide derivative and use thereof as medicine | MITSUBISHI TANABE PHARMA CORP | 2013-03-13 | — | — | CN | disclosed |
| CN-102239152-A | Novel amide derivative and use thereof as medicine | MITSUBISHI TANABE PHARMA CORP | 2011-11-09 | — | — | CN | disclosed |