Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.41 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27806570 | 1.00 | HDAC3 (0.41) | HDAC3HDAC1HDAC2NCOR2HDAC8 | |
| SCHEMBL31158568 | 0.83 | TSHR (0.50) | HDAC3HDAC1HDAC2NCOR2HDAC8 | |
| SCHEMBL34460861 | 0.83 | TSHR (0.50) | HDAC3HDAC1HDAC2NCOR2HDAC8 | |
| SCHEMBL27848554 | 0.78 | ALDH1A1 (0.31) | ALDH1A1L3MBTL1 | |
| SCHEMBL1548278 | 0.78 | ALDH1A1 (0.54) | ALDH1A1HSD17B10KDM4EADORA3AR | |
| Aminorex SCHEMBL123039 | 0.78 | TSHR (0.45) | HDAC3HDAC1HDAC2NCOR2HDAC8 | |
| SCHEMBL8303539 | 0.75 | KDM1A (0.39) | ALDH1A1HSD17B10KDM4EADORA3AR | |
| SCHEMBL27924990 | 0.75 | MAOA (0.41) | ALDH1A1HSD17B10KDM4EL3MBTL1ADORA3 | |
| SCHEMBL8303541 | 0.75 | KDM1A (0.39) | ALDH1A1HSD17B10KDM4EADORA3AR | |
| SCHEMBL27924991 | 0.75 | MAOA (0.41) | ALDH1A1HSD17B10KDM4EL3MBTL1ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101973953-B | Method for synthesizing chiral oxazoline | MEI LUO | 2012-04-18 | — | — | CN | claimed |