SCHEMBL27849335

SCHEMBL27849335

CO[Si](OC)(OC)C(C)c1ccc(I)cc1

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ACACB O00763 1/20 0.33
CYP1A2 P05177 1/20 0.31
CYP2D6 P10635 1/20 0.31
ESR1 P03372 1/20 0.30
PDCD1 Q15116 1/20 0.30
ESR2 Q92731 1/20 0.30
CD274 Q9NZQ7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL235152 0.89 ESR1 (0.36) ESR1PDCD1ESR2CD274
SCHEMBL928392 0.83 ESR1 (0.30) ESR1PDCD1ESR2CD274
SCHEMBL27147585 0.82 CYP17A1 (0.34) ESR1PDCD1ESR2CD274
SCHEMBL760246 0.80 ESR1 (0.52) CYP1A2CYP2D6ESR1PDCD1ESR2
SCHEMBL22551505 0.78 ESR1 (0.30) ESR1PDCD1ESR2CD274
SCHEMBL27866274 0.78 CYP1A2 (0.35) CYP1A2
SCHEMBL929334 0.78 ESR1 (0.30) ESR1PDCD1ESR2CD274
SCHEMBL22551470 0.78 ESR1 (0.30) ESR1PDCD1ESR2CD274
SCHEMBL927965 0.78 ESR1 (0.30) ESR1PDCD1ESR2CD274
SCHEMBL926685 0.78 IDO1 (0.33) CYP1A2CYP2D6ESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102432924-A Rubber composition, method of making the same, and articles made therefrom MOMENTIVE PERFORMANCE MAT INC 2012-05-02 CN disclosed