SCHEMBL22551470

SCHEMBL22551470

CO[Si](OC)(OC)C(C)c1ccc(C(C)S)cc1

nearest known ligand 0.30

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.30
PDCD1 Q15116 1/20 0.30
ESR2 Q92731 1/20 0.30
CD274 Q9NZQ7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL235152 0.89 ESR1 (0.36) ESR1PDCD1ESR2CD274
SCHEMBL22551505 0.83 ESR1 (0.30) ESR1PDCD1ESR2CD274
SCHEMBL27147585 0.82 CYP17A1 (0.34) ESR1PDCD1ESR2CD274
SCHEMBL760246 0.80 ESR1 (0.52) ESR1PDCD1ESR2CD274
SCHEMBL928392 0.78 ESR1 (0.30) ESR1PDCD1ESR2CD274
SCHEMBL927965 0.78 ESR1 (0.30) ESR1PDCD1ESR2CD274
SCHEMBL27849335 0.78 ACACB (0.33) ESR1PDCD1ESR2CD274
SCHEMBL27866274 0.78 CYP1A2 (0.35)
SCHEMBL929334 0.78 ESR1 (0.30) ESR1PDCD1ESR2CD274
SCHEMBL927436 0.78 IDO1 (0.33) ESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11739184-B2 Polysiloxazane compound having alkoxysilyl group, process for producing same, and composition and cured product including same SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-08-29 US disclosed
US-11708460-B2 Alkoxysilyl group-containing organic silazane compound, method for producing same, composition containing same and cured product SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-07-25 US disclosed
EP-3798252-B1 POLYSILOXAZANE COMPOUND HAVING ALKOXYSILYL GROUP, PROCESS FOR PRODUCING SAME, AND COMPOSITION AND CURED PRODUCT INCLUDING SAME SHINETSU CHEMICAL CO (JP) 2022-06-29 EP disclosed
US-20210095079-A1 POLYSILOXAZANE COMPOUND HAVING ALKOXYSILYL GROUP, PROCESS FOR PRODUCING SAME, AND COMPOSITION AND CURED PRODUCT INCLUDING SAME SHIN-ETSU CHEMICAL CO., LTD. (JP) 2021-04-01 US disclosed
EP-3798252-A1 POLYSILOXAZANE COMPOUND HAVING ALKOXYSILYL GROUP, PROCESS FOR PRODUCING SAME, AND COMPOSITION AND CURED PRODUCT INCLUDING SAME Shin-Etsu Chemical Co., Ltd. (JP) 2021-03-31 EP disclosed
CN-111825710-A Organosilazane compounds containing alkoxysilyl groups, process for their preparation, compositions containing them and cured products 信越化学工业株式会社 2020-10-27 CN disclosed
US-20200332071-A1 ALKOXYSILYL GROUP-CONTAINING ORGANIC SILAZANE COMPOUND, METHOD FOR PRODUCING SAME, COMPOSITION CONTAINING SAME AND CURED PRODUCT SHIN-ETSU CHEMICAL CO., LTD. (JP) 2020-10-22 US disclosed
EP-3725822-A1 ALKOXYSILYL GROUP-CONTAINING ORGANIC SILAZANE COMPOUND, METHOD FOR PRODUCING SAME, COMPOSITION CONTAINING SAME AND CURED PRODUCT Shin-Etsu Chemical Co., Ltd. (JP) 2020-10-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11708460-B2 Alkoxysilyl group-containing organic silazane compound, method for producing same, composition containing same and cured product OR10J3, ALKBH1, ALKBH2 ESR1 649/4885PDCD1 4482/4885ESR2 1657/4885
US-20200332071-A1 ALKOXYSILYL GROUP-CONTAINING ORGANIC SILAZANE COMPOUND, METHOD FOR PRODUCING SAME, COMPOSITION CONTAINING SAME AND CURED PRODUCT OR10J3, ALKBH1, ALKBH2 ESR1 649/4885PDCD1 4482/4885ESR2 1657/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.