Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 11/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | F13A1 | P00488 | 1/20 | 0.51 |
| ▸ | TGM1 | P22735 | 1/20 | 0.51 |
| ▸ | TGM3 | Q08188 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | ITK | Q08881 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | FYN | P06241 | 1/20 | 0.43 |
| ▸ | SRC | P12931 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29054310 | 0.87 | TGM2 (0.66) | TGM2LMNAF13A1TGM1TGM3 | |
| SCHEMBL6481884 | 0.87 | TGM2 (0.66) | TGM2LMNAF13A1TGM1TGM3 | |
| SCHEMBL7785803 | 0.87 | TGM2 (0.66) | TGM2LMNAF13A1TGM1TGM3 | |
| Acetic Acid SCHEMBL11194307 | 0.83 | TGM2 (0.62) | TGM2LMNAF13A1TGM1TGM3 | |
| Aniline SCHEMBL28025728 | 0.82 | TGM2 (0.81) | TGM2LMNAF13A1TGM1TGM3 | |
| SCHEMBL20469814 | 0.82 | TGM2 (0.59) | TGM2LMNAF13A1TGM1TGM3 | |
| SCHEMBL6430031 | 0.79 | TGM2 (0.64) | TGM2LMNAF13A1TGM1TGM3 | |
| Dioxane SCHEMBL29080479 | 0.78 | TGM2 (0.54) | TGM2LMNAF13A1TGM1TGM3 | |
| Pyridine SCHEMBL27849476 | 0.77 | JAK3 (0.43) | TGM2LMNAMAPTEGFRITK | |
| SCHEMBL439369 | 0.77 | TGM2 (0.79) | TGM2LMNAF13A1TGM1TGM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102421754-A | Acrylamide derivative and use thereof in manufacture of medicament | BEIJING JIASHILIANBO PHARM SCI & TECH CO LTD | 2012-04-18 | — | — | CN | disclosed |