Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 11/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | F13A1 | P00488 | 2/20 | 0.59 |
| ▸ | TGM1 | P22735 | 2/20 | 0.59 |
| ▸ | TGM3 | Q08188 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.50 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.50 |
| ▸ | TDP2 | O95551 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | APEX1 | P27695 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
| ▸ | TEK | Q02763 | 1/20 | 0.47 |
| ▸ | THRA | P10827 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7785803 | 0.94 | TGM2 (0.66) | TGM2LMNAF13A1TGM1TGM3 | |
| SCHEMBL6481884 | 0.94 | TGM2 (0.66) | TGM2LMNAF13A1TGM1TGM3 | |
| SCHEMBL29054310 | 0.94 | TGM2 (0.66) | TGM2LMNAF13A1TGM1TGM3 | |
| Acetic Acid SCHEMBL11194307 | 0.87 | TGM2 (0.62) | TGM2LMNAF13A1TGM1TGM3 | |
| Dioxane SCHEMBL29080479 | 0.84 | TGM2 (0.54) | TGM2LMNAF13A1TGM1TGM3 | |
| SCHEMBL439369 | 0.84 | TGM2 (0.79) | TGM2LMNAF13A1TGM1TGM3 | |
| SCHEMBL1383664 | 0.83 | TGM2 (0.78) | TGM2LMNAF13A1TGM1TGM3 | |
| SCHEMBL964754 | 0.83 | TGM2 (0.64) | TGM2LMNAF13A1TGM1TGM3 | |
| Pyridine SCHEMBL27849477 | 0.82 | TGM2 (0.59) | TGM2LMNAF13A1TGM1TGM3 | |
| Aniline SCHEMBL28025728 | 0.81 | TGM2 (0.81) | TGM2LMNAF13A1TGM1TGM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018144869-A1 | COMPOSITONS AND METHODS FOR MODULATING UBA5 | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2018-08-09 | — | — | WO | disclosed |
| CN-105683257-B | Addition-fragmentation oligomers containing allyl disulfide | 3M创新有限公司 | 2018-02-13 | — | — | CN | disclosed |