Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 13/20 | 0.66 |
| ▸ | F13A1 | P00488 | 3/20 | 0.66 |
| ▸ | TGM1 | P22735 | 3/20 | 0.66 |
| ▸ | LMNA | P02545 | 2/20 | 0.66 |
| ▸ | TGM3 | Q08188 | 1/20 | 0.66 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | APEX1 | P27695 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | THRA | P10827 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29054310 | 1.00 | TGM2 (0.66) | TGM2F13A1TGM1LMNATGM3 | |
| SCHEMBL6481884 | 1.00 | TGM2 (0.66) | TGM2F13A1TGM1LMNATGM3 | |
| SCHEMBL20469814 | 0.94 | TGM2 (0.59) | TGM2F13A1TGM1LMNATGM3 | |
| Acetic Acid SCHEMBL11194307 | 0.93 | TGM2 (0.62) | TGM2F13A1TGM1LMNATGM3 | |
| Dioxane SCHEMBL29080479 | 0.89 | TGM2 (0.54) | TGM2F13A1TGM1LMNATGM3 | |
| SCHEMBL439369 | 0.89 | TGM2 (0.79) | TGM2F13A1TGM1LMNATGM3 | |
| SCHEMBL964754 | 0.88 | TGM2 (0.64) | TGM2F13A1TGM1LMNATGM3 | |
| Pyridine SCHEMBL27849477 | 0.87 | TGM2 (0.59) | TGM2F13A1TGM1LMNATGM3 | |
| Aniline SCHEMBL28025728 | 0.86 | TGM2 (0.81) | TGM2F13A1TGM1LMNATGM3 | |
| SCHEMBL7845225 | 0.83 | HPGD (0.56) | TGM2F13A1TGM1LMNATGM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1137633-A2 | ACETAMIDE AND SUBSTITUTED ACETAMIDE-CONTAINING THIOUREA INHIBITORS OF HERPES VIRUSES | AMERICAN HOME PRODUCTS CORPORATION (US) | 2001-10-04 | — | — | EP | disclosed |
| WO-2000034237-A2 | ACETAMIDE AND SUBSTITUTED ACETAMIDE-CONTAINING THIOUREA INHIBITORS OF HERPES VIRUSES | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-06-15 | — | — | WO | disclosed |