Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | DPP4 | P27487 | 2/20 | 0.44 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27831285 | 0.87 | CCR2 (0.41) | MEN1KMT2AALDH1A1DPP4 | |
| SCHEMBL27831264 | 0.82 | OPRM1 (0.44) | KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL27831257 | 0.81 | OPRM1 (0.48) | MEN1KMT2ATSHRSMN1; SMN2LMNA | |
| SCHEMBL27849843 | 0.81 | KDM1A (0.40) | MEN1KMT2AALDH1A1KDM4ETSHR | |
| Biphenyl SCHEMBL27849809 | 0.80 | MAPT (0.47) | MEN1KMT2AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL27831268 | 0.76 | USP30 (0.41) | MEN1KMT2AALDH1A1KDM4ETSHR | |
| SCHEMBL27849787 | 0.75 | DPP8 (0.40) | LMNADPP4DPP8 | |
| SCHEMBL27831318 | 0.75 | CHRM2 (0.39) | ALDH1A1POLB | |
| SCHEMBL27831365 | 0.73 | SIGMAR1 (0.48) | ALDH1A1KDM4EPOLBGAA | |
| SCHEMBL2357966 | 0.73 | MEN1 (0.56) | MEN1KMT2AALDH1A1KDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102239146-A | Novel compounds as calcium channel blockers | ABBOTT LAB | 2011-11-09 | — | — | CN | claimed |
| CN-102239146-A | Novel compounds as calcium channel blockers | ABBOTT LAB | 2011-11-09 | — | — | CN | disclosed |