Known targets — ChEMBL curated mechanism
FGFR1FGFR2FGFR3FGFR4FLT1FLT4KDRPDGFRAPDGFRB
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7289366 | 0.87 | — | — | |
| Piperazine SCHEMBL28124495 | 0.85 | — | — | |
| SCHEMBL15556975 | 0.75 | — | — | |
| Tert-Butyl Formate SCHEMBL28839953 | 0.74 | TDP1 (0.39) | — | |
| SCHEMBL27837272 | 0.74 | LMNA (0.30) | — | |
| Pyridine SCHEMBL28333567 | 0.73 | CHRM2 (0.31) | — | |
| SCHEMBL15556972 | 0.71 | — | — | |
| Piperazine SCHEMBL572783 | 0.70 | TSHR (0.42) | — | |
| Piperazine SCHEMBL1171029 | 0.70 | TSHR (0.42) | — | |
| Piperazine SCHEMBL28176112 | 0.70 | TSHR (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103998047-A | Local modulation of tissues and cells to enhance therapeutic effects including renal denervation | MERCATOR MEDSYSTEMS INC | 2014-08-20 | — | — | CN | claimed |
| CN-107383158-A | The method for purifying pegylated protein | 诺沃—诺迪斯克保健股份有限公司 | 2017-11-24 | — | — | CN | disclosed |
| CN-104066438-A | Anti-diabetic compounds | PFIZER | 2014-09-24 | — | — | CN | disclosed |
| CN-103491898-A | Biomatrix scaffolds for industrial scale dispersion | UNIV NORTH CAROLINA CHAPEL HILL | 2014-01-01 | — | — | CN | disclosed |
| CN-103249404-A | Biological matrix scaffold | UNIV NORTH CAROLINA CHAPEL HILL | 2013-08-14 | — | — | CN | disclosed |
| CN-103068496-A | Supercritical noble gases and cleaning methods | EMPIRE TECHNOLOGY DEV LLC | 2013-04-24 | — | — | CN | disclosed |
| CN-102458374-A | Skin delivery compositions comprising active agent-calcium phosphate particle complexes and methods of use thereof | LAB SKIN CARE INC | 2012-05-16 | — | — | CN | disclosed |