Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 5/20 | 0.39 |
| ▸ | ICMT | O60725 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 2/20 | 0.35 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27853096 | 0.84 | CYP2C9 (0.42) | SYKGAARAB9ACYP2E1CYP3A4 | |
| SCHEMBL4870253 | 0.82 | SYK (0.47) | SYKICMTNPC1POLBGAA | |
| SCHEMBL27853098 | 0.82 | CA2 (0.39) | SYKCYP2E1CYP3A4CYP2A6CYP2C9 | |
| SCHEMBL27853099 | 0.81 | CA2 (0.38) | SYKNPC1GAARAB9ACYP2E1 | |
| SCHEMBL27853097 | 0.81 | CA12 (0.38) | SYKCYP2E1CYP3A4CYP2A6CYP2C9 | |
| SCHEMBL28791762 | 0.81 | CA12 (0.40) | SYKCYP2E1CYP3A4CYP2A6CYP2C9 | |
| SCHEMBL27835085 | 0.81 | CYP11B2 (0.38) | SYKCYP2E1CYP3A4CYP2A6CYP2C9 | |
| SCHEMBL27835096 | 0.81 | EP300 (0.36) | SYKCYP2E1CYP3A4CYP2A6CYP2C9 | |
| SCHEMBL27853094 | 0.77 | CA12 (0.37) | SYKCYP2E1CYP3A4CYP2A6CYP2C9 | |
| SCHEMBL27835093 | 0.76 | CYP2A6 (0.62) | CYP2E1CYP3A4CYP2A6CYP2C9CYP2B6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102030738-A | Novel imidazole compound, preparation method and use thereof | JUBILANT ORGANOSYS LTD | 2011-04-27 | — | — | CN | claimed |
| CN-102030738-A | Novel imidazole compound, preparation method and use thereof | JUBILANT ORGANOSYS LTD | 2011-04-27 | — | — | CN | disclosed |