Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | HPGDS | O60760 | 1/20 | 0.36 |
| ▸ | CYP2E1 | P05181 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | MET | P08581 | 1/20 | 0.32 |
| ▸ | SYK | P43405 | 1/20 | 0.32 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.32 |
| ▸ | KDM5A | P29375 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27853098 | 0.85 | CA2 (0.39) | CA12CA1CA2CA9HPGDS | |
| SCHEMBL27835085 | 0.84 | CYP11B2 (0.38) | CA12CA1CA2CA9HPGDS | |
| SCHEMBL27853096 | 0.84 | CYP2C9 (0.42) | CA12CA1CA2CA9HPGDS | |
| SCHEMBL27853099 | 0.84 | CA2 (0.38) | CA12CA1CA2CA9HPGDS | |
| SCHEMBL28791762 | 0.84 | CA12 (0.40) | CA12CA1CA2CA9HPGDS | |
| SCHEMBL14268982 | 0.81 | CYP2E1 (0.43) | HPGDSCYP2E1CYP3A4CYP2A6CYP2C9 | |
| SCHEMBL4869517 | 0.81 | PIK3CD (0.38) | HPGDSCYP2E1CYP3A4CYP2A6CYP2C9 | |
| SCHEMBL27853095 | 0.81 | SYK (0.39) | CA12CA1CA2CA9CYP2E1 | |
| SCHEMBL27835096 | 0.81 | EP300 (0.36) | CA12CA1CA2CA9HPGDS | |
| SCHEMBL27853094 | 0.80 | CA12 (0.37) | CA12CA1CA2CA9HPGDS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102030738-A | Novel imidazole compound, preparation method and use thereof | JUBILANT ORGANOSYS LTD | 2011-04-27 | — | — | CN | claimed |
| CN-102030738-A | Novel imidazole compound, preparation method and use thereof | JUBILANT ORGANOSYS LTD | 2011-04-27 | — | — | CN | disclosed |