Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 4/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 6/20 | 0.39 |
| ▸ | PPARA | Q07869 | 6/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7691212 | 0.81 | TDP1 (0.47) | SLC6A4SLC6A2SLC6A3TDP1S1PR4 | |
| SCHEMBL27870121 | 0.80 | TSHR (0.42) | SLC6A4SLC6A2SLC6A3HPGDTSHR | |
| SCHEMBL12126657 | 0.76 | TSHR (0.51) | SLC6A4SLC6A2KCNH2SLC6A3TDP1 | |
| SCHEMBL27853319 | 0.75 | SLC6A4 (0.44) | SLC6A4SLC6A2KCNH2SLC6A3S1PR4 | |
| Dimethylamine SCHEMBL28476059 | 0.74 | SLC6A4 (0.46) | SLC6A4SLC6A2KCNH2SLC6A3PPARG | |
| SCHEMBL7499255 | 0.73 | L3MBTL1 (0.47) | TDP1HPGD | |
| SCHEMBL27870137 | 0.73 | HTR2A (0.43) | SLC6A4KCNH2TSHRHTR2A | |
| SCHEMBL1765256 | 0.72 | LMNA (0.50) | SLC6A4SLC6A2KCNH2SLC6A3PPARG | |
| SCHEMBL1023561 | 0.71 | LMNA (0.48) | SLC6A4SLC6A2KCNH2SLC6A3PPARG | |
| SCHEMBL24252062 | 0.69 | SLC6A4 (0.44) | SLC6A4SLC6A2KCNH2SLC6A3PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102471258-A | 3-phenoxymethylpyrrolidine compounds | THERAVANCE INC | 2012-05-23 | — | — | CN | disclosed |