Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | XBP1 | P17861 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | RHEB | Q15382 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9363133 | 0.84 | L3MBTL1 (0.44) | L3MBTL1TDP1NFE2L2HTTNPSR1 | |
| SCHEMBL9317193 | 0.77 | TSHR (0.41) | TDP1NPSR1ALDH1A1MAPTMEN1 | |
| SCHEMBL5778963 | 0.77 | CA1 (0.56) | L3MBTL1TDP1NFE2L2HTTALDH1A1 | |
| SCHEMBL1321164 | 0.76 | NFE2L2 (0.48) | L3MBTL1TDP1NFE2L2ALDH1A1ESR1 | |
| SCHEMBL1702501 | 0.75 | CA2 (0.50) | L3MBTL1TDP1NPSR1ALDH1A1MAPT | |
| SCHEMBL7494685 | 0.75 | L3MBTL1 (0.41) | L3MBTL1TDP1NPSR1ALDH1A1CXCL8 | |
| SCHEMBL4065849 | 0.75 | ALDH1A1 (0.55) | L3MBTL1TDP1HTTALDH1A1MAPT | |
| SCHEMBL27853333 | 0.73 | SLC6A4 (0.43) | TDP1HPGD | |
| SCHEMBL8152541 | 0.72 | CYP1A2 (0.41) | TDP1HTTNPSR1ALDH1A1MAPT | |
| SCHEMBL3861740 | 0.72 | HTR1B (0.47) | TDP1ALDH1A1HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102471258-A | 3-phenoxymethylpyrrolidine compounds | THERAVANCE INC | 2012-05-23 | — | — | CN | disclosed |
| EP-0760362-B1 | DIAMINOMETHYLIDENE DERIVATIVE | NISSHIN SEIFUN GROUP INC (JP) | 2002-08-14 | — | — | EP | disclosed |
| EP-0760368-B1 | PYRIMIDINE DERIVATIVES | NISSHIN FLOUR MILLING CO (JP) | 1999-07-28 | — | — | EP | disclosed |
| US-5753654-A | GASTROINTESTINAL DISORDERS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1998-05-19 | — | — | US | disclosed |
| US-5736550-A | TREATMENT OF GASTROINTESTINAL TRACT DISORDERS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1998-04-07 | — | — | US | disclosed |
| EP-0760362-A1 | NOVEL DIAMINOMETHYLIDENE DERIVATIVE | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1997-03-05 | — | — | EP | disclosed |
| EP-0760368-A1 | NOVEL PYRIMIDINE DERIVATIVE | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1997-03-05 | — | — | EP | disclosed |
| US-5192767-A | Nonphytotoxic | BASF AKTIENGESELLSCHAFT (DE) | 1993-03-09 | — | — | US | disclosed |
| EP-0311907-A2 | 3-Substituted pyridines and fungicides containing them | BASF Aktiengesellschaft (DE) | 1989-04-19 | — | — | EP | disclosed |