Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 3/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 2/20 | 0.36 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.35 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.35 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27838563 | 1.00 | ACHE (0.39) | ACHETRPM8HTR2AHTR2CHTR2B | |
| SCHEMBL21954384 | 0.82 | ACHE (0.45) | ACHETRPM8HTR2AHTR2CHTR2B | |
| SCHEMBL784422 | 0.80 | HTR2A (0.41) | ACHEHTR2AHTR2CHTR2BPTGDR | |
| SCHEMBL18497279 | 0.79 | ACHE (0.40) | ACHETRPM8HTR2AHTR2CHTR2B | |
| SCHEMBL28300301 | 0.78 | TRPM8 (0.51) | TRPM8HTR2AIDO1 | |
| SCHEMBL28224648 | 0.78 | TRPM8 (0.51) | TRPM8HTR2AIDO1 | |
| SCHEMBL3645107 | 0.74 | ACHE (0.51) | ACHEHTR2AHTR2CHTR2BIDO1 | |
| SCHEMBL1576021 | 0.74 | ACHE (0.51) | ACHEHTR2AHTR2CHTR2BIDO1 | |
| SCHEMBL30896364 | 0.74 | ACHE (0.51) | ACHEHTR2AHTR2CHTR2BIDO1 | |
| SCHEMBL19521148 | 0.74 | RAB9A (0.48) | ACHEHTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103097354-A | Substituted benzamide compounds | GRUENENTHAL CHEMIE | 2013-05-08 | — | — | CN | disclosed |
| CN-102365276-A | Substituted spiro-amide compounds | GRUENENTHAL GMBH | 2012-02-29 | — | — | CN | disclosed |