Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27856475 | 0.80 | USP2 (0.54) | USP2TSHRALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL8219313 | 0.78 | POLB (0.49) | TSHRALDH1A1KMT2AMEN1CYP2C9 | |
| SCHEMBL6518443 | 0.78 | POLB (0.49) | TSHRALDH1A1KMT2AMEN1CYP2C9 | |
| SCHEMBL6523714 | 0.78 | POLB (0.49) | TSHRALDH1A1KMT2AMEN1CYP2C9 | |
| SCHEMBL27856508 | 0.68 | CYP2C19 (0.37) | USP2ALDH1A1KMT2AKDM4EMEN1 | |
| SCHEMBL27762537 | 0.66 | DPP4 (0.36) | USP2TSHRALDH1A1KMT2AKDM4E | |
| SCHEMBL6522988 | 0.66 | ALDH1A1 (0.48) | TSHRALDH1A1KMT2APOLB | |
| SCHEMBL8224388 | 0.66 | ALDH1A1 (0.48) | TSHRALDH1A1KMT2APOLB | |
| SCHEMBL6518007 | 0.66 | ALDH1A1 (0.48) | TSHRALDH1A1KMT2APOLB | |
| SCHEMBL8219207 | 0.65 | FAAH (0.49) | ALDH1A1KMT2ACYP2C9SMN1; SMN2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102498099-A | HSL inhibitors useful in the treatment of diabetes | HOFFMANN LA ROCHE | 2012-06-13 | — | — | CN | disclosed |