Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 10/20 | 0.57 |
| ▸ | FDPS | P14324 | 1/20 | 0.53 |
| ▸ | ACHE | P22303 | 6/20 | 0.52 |
| ▸ | BCHE | P06276 | 5/20 | 0.52 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | EGFR | P00533 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10585056 | 0.98 | APP (0.56) | APPFDPSACHEBCHEPDE10A | |
| SCHEMBL27873802 | 0.91 | HPGD (0.59) | APPFDPSACHEBCHEPDE10A | |
| SCHEMBL5135084 | 0.88 | MRGPRX1 (0.53) | APPFDPSPDE10AHDAC3HDAC1 | |
| SCHEMBL27857007 | 0.85 | RAD52 (0.56) | APPFDPSACHEBCHEHDAC3 | |
| SCHEMBL7683833 | 0.80 | FDPS (0.56) | APPFDPSACHEBCHEPDE10A | |
| SCHEMBL17186572 | 0.78 | APP (0.54) | APPACHEBCHEHDAC3HDAC1 | |
| SCHEMBL3337103 | 0.77 | FDPS (0.53) | FDPSPDE10ASLC2A1RAB9ANPC1 | |
| SCHEMBL27485928 | 0.77 | TLR8 (0.54) | FDPSBCHEPDE10ANPC1EGFR | |
| SCHEMBL11477682 | 0.77 | FDPS (0.57) | FDPSPDE10APCSK9KDM4EALDH1A1 | |
| SCHEMBL22151175 | 0.77 | APP (0.64) | APPACHEBCHERAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102491949-A | Method for synthesizing 2-(N-alkyl) aminopyrimidine derivatives by means of N-alkylation | UNIV NANJING SCIENCE & TECH | 2012-06-13 | — | — | CN | disclosed |