Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | FDPS | P14324 | 1/20 | 0.51 |
| ▸ | APP | P05067 | 2/20 | 0.48 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.47 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | CTSC | P53634 | 1/20 | 0.46 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | GBA1 | P04062 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | IGF1R | P08069 | 1/20 | 0.43 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27857052 | 0.91 | APP (0.57) | HPGDFDPSAPPPDE10APCSK9 | |
| Hydrochloric Acid SCHEMBL10585056 | 0.89 | APP (0.56) | HPGDFDPSAPPPDE10APCSK9 | |
| SCHEMBL27857007 | 0.82 | RAD52 (0.56) | FDPSAPPPCSK9BCHEACHE | |
| SCHEMBL27485928 | 0.81 | TLR8 (0.54) | FDPSPDE10APCSK9BCHE | |
| SCHEMBL11477682 | 0.81 | FDPS (0.57) | HPGDFDPSMKNK2PDE10APCSK9 | |
| SCHEMBL2578318 | 0.80 | FDPS (0.52) | FDPSPDE10APCSK9BCHE | |
| SCHEMBL5135084 | 0.79 | MRGPRX1 (0.53) | FDPSAPPMKNK2PDE10ACYP1A2 | |
| SCHEMBL27857097 | 0.79 | FDPS (0.51) | FDPSPDE10APCSK9GBA1 | |
| SCHEMBL27857084 | 0.79 | FDPS (0.51) | FDPSPDE10APCSK9GBA1 | |
| SCHEMBL7683833 | 0.78 | FDPS (0.56) | FDPSAPPPDE10APCSK9BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102491949-A | Method for synthesizing 2-(N-alkyl) aminopyrimidine derivatives by means of N-alkylation | UNIV NANJING SCIENCE & TECH | 2012-06-13 | — | — | CN | disclosed |