Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX1 | Q96LB2 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.51 |
| ▸ | FDPS | P14324 | 1/20 | 0.49 |
| ▸ | MKNK2 | Q9HBH9 | 3/20 | 0.47 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.47 |
| ▸ | MYLK | Q15746 | 1/20 | 0.46 |
| ▸ | APP | P05067 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27857052 | 0.88 | APP (0.57) | HTTALDH1A1LMNAMAPTHDAC3 | |
| Hydrochloric Acid SCHEMBL10585056 | 0.87 | APP (0.56) | HTTALDH1A1LMNAMAPTHDAC3 | |
| SCHEMBL27873802 | 0.79 | HPGD (0.59) | CYP1A2CYP2D6CYP2C19PDE10AFDPS | |
| SCHEMBL7683833 | 0.75 | FDPS (0.56) | ALDH1A1PDE10AFDPSAPP | |
| SCHEMBL4376041 | 0.74 | APP (0.49) | MRGPRX1HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL27857007 | 0.73 | RAD52 (0.56) | ALDH1A1LMNAMAPTHDAC3HDAC1 | |
| SCHEMBL11477682 | 0.73 | FDPS (0.57) | ALDH1A1PDE10AFDPSMKNK2MKNK1 | |
| SCHEMBL27485928 | 0.73 | TLR8 (0.54) | PDE10AFDPS | |
| SCHEMBL3337103 | 0.73 | FDPS (0.53) | CYP2C19PDE10AFDPSMKNK2MKNK1 | |
| SCHEMBL31141666 | 0.72 | HDAC3 (0.58) | MRGPRX1HTTALDH1A1LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8309133-B2 | Nanoparticulate quinazoline derivative formulations | ALKERMES PHARMA IRELAND LIMITED (IE) | 2012-11-13 | — | — | US | disclosed |
| EP-1871345-B1 | NANOPARTICULATE ERLOTINIB FORMULATIONS | ELAN PHARMA INT LTD (IE) | 2012-08-01 | — | — | EP | disclosed |
| EP-1871345-A1 | NANOPARTICULATE QUINAZOLINE DERIVATIVE FORMULATIONS | Elan Pharma International Limited (IE) | 2008-01-02 | — | — | EP | disclosed |
| US-20060246142-A1 | Nanoparticulate quinazoline derivative formulations | ELAN PHARMA INTERNATIONAL, LIMITED | 2006-11-02 | — | — | US | disclosed |
| WO-2006110811-A1 | NANOPARTICULATE QUINAZOLINE DERIVATIVE FORMULATIONS | ELAN PHARMA INTERNATIONAL LIMITED (IE) | 2006-10-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060246142-A1 | Nanoparticulate quinazoline derivative formulations | KRAS, NRAS, ABL1 | MRGPRX1 2661/4885HTT 619/4885ALDH1A1 2763/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.