Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 4/20 | 0.59 |
| ▸ | MDM4 | O15151 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | CTSS | P25774 | 1/20 | 0.44 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29471035 | 0.96 | CASP3 (0.61) | CASP3MDM4TP53KMT2APIN1 | |
| SCHEMBL29068308 | 0.94 | CASP3 (0.64) | CASP3MDM4TP53KMT2APIN1 | |
| SCHEMBL29068310 | 0.94 | CASP3 (0.64) | CASP3MDM4TP53KMT2APIN1 | |
| SCHEMBL30307097 | 0.92 | CASP3 (0.60) | CASP3MDM4TP53KMT2APIN1 | |
| SCHEMBL178791 | 0.92 | CASP3 (0.60) | CASP3MDM4TP53KMT2APIN1 | |
| SCHEMBL29375252 | 0.92 | CASP3 (0.60) | CASP3MDM4TP53KMT2APIN1 | |
| SCHEMBL799720 | 0.92 | CASP3 (0.60) | CASP3MDM4TP53KMT2APIN1 | |
| SCHEMBL31697682 | 0.92 | CASP3 (0.60) | CASP3MDM4TP53KMT2APIN1 | |
| SCHEMBL29356434 | 0.92 | CASP3 (0.60) | CASP3MDM4TP53KMT2APIN1 | |
| SCHEMBL120703 | 0.92 | CASP3 (0.60) | CASP3MDM4TP53KMT2APIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102241736-B | Method for synthesizing key intermediate of antitumour medicament Romidepsi | JASUN PHARMCHEM CO LTD | 2013-06-26 | — | — | CN | disclosed |
| CN-102241736-A | Method for synthesizing key intermediate of antitumour medicament Romidepsi | JASUN PHARMCHEM CO LTD | 2011-11-16 | — | — | CN | disclosed |