SCHEMBL29375252

SCHEMBL29375252

CC(C)[C@@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)O

nearest known ligand 0.60

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CASP3 P42574 4/20 0.60
KMT2A Q03164 2/20 0.52
MDM4 O15151 2/20 0.52
TP53 P04637 2/20 0.52
EPHX2 P34913 1/20 0.49
PIN1 Q13526 1/20 0.48
MDM2 Q00987 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29356434 1.00 CASP3 (0.60) CASP3KMT2AMDM4TP53EPHX2
SCHEMBL30307097 1.00 CASP3 (0.60) CASP3KMT2AMDM4TP53EPHX2
SCHEMBL120703 1.00 CASP3 (0.60) CASP3KMT2AMDM4TP53EPHX2
SCHEMBL799720 1.00 CASP3 (0.60) CASP3KMT2AMDM4TP53EPHX2
SCHEMBL178791 1.00 CASP3 (0.60) CASP3KMT2AMDM4TP53EPHX2
SCHEMBL29423588 1.00 CASP3 (0.60) CASP3KMT2AMDM4TP53EPHX2
SCHEMBL31697682 1.00 CASP3 (0.60) CASP3KMT2AMDM4TP53EPHX2
Hydrochloric Acid SCHEMBL6779156 0.99 CASP3 (0.59) CASP3KMT2AMDM4TP53EPHX2
Fluoride SCHEMBL7158848 0.99 CASP3 (0.59) CASP3KMT2AMDM4TP53EPHX2
SCHEMBL29068310 0.95 CASP3 (0.64) CASP3KMT2AMDM4TP53EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 140 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118937550-A Method for separating Fmoc-L-Val-OH and Fmoc-D-Val-OH in reverse phase 贵州医科大学附属医院 2024-11-12 CN claimed
CN-118829254-A Perovskite solar cell preparation method and perovskite solar cell 广东明阳薄膜科技有限公司 2024-10-22 CN claimed
CN-111333697-B Synthesis method of romidepsin 深圳翰宇药业股份有限公司 2022-03-08 CN claimed
CN-122036842-A Cathepsin B-sensitive fatty acid-irinotecan prodrug and albumin nanoparticle thereof, and preparation method and application thereof 沈阳药科大学 2026-05-15 CN disclosed
EP-4720097-A1 PEPTIDES WITH LIPOLYTIC, ANTI-LIPOGENIC, ANTIFIBROTIC AND ANTI-INFLAMMATORY ACTIVITY Fundació Hospital Universitari Vall d'Hebron - Institut de Recerca (ES) 2026-04-08 EP disclosed
EP-3455234-B1 SECO MACROLIDE COMPOUNDS SELVITA D O O (HR) 2026-04-01 EP disclosed
US-20260083852-A1 PROTEOGLYCAN MIMETICS FOR ENHANCED WOUND HEALING, ANGIOGENESIS, AND VASCULAR REPAIR UNIV CALIFORNIA (US) 2026-03-26 US disclosed
EP-3604326-B1 PEPTIDE COMPOUND AND METHOD FOR PRODUCING SAME, COMPOSITION FOR SCREENING USE, AND METHOD FOR SELECTING PEPTIDE COMPOUND FUJIFILM CORP (JP) 2026-01-07 EP disclosed
US-20260001928-A1 CRF2 RECEPTOR AGONISTS AND THEIR USE IN THERAPY CORTERIA PHARMACEUTICALS (FR) 2026-01-01 US disclosed
EP-4482578-B1 CRF2 RECEPTOR AGONISTS AND THEIR USE IN THERAPY CORTERIA PHARMACEUTICALS (FR) 2025-12-24 EP disclosed
US-12485182-B2 Proteoglycan mimetics for enhanced wound healing, angiogenesis, and vascular repair THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2025-12-02 US disclosed
US-11319347-B2 Peptide compound and method for producing same, composition for screening use, and method for selecting peptide compound FUJIFILM CORPORATION (JP) 2022-05-03 US disclosed
WO-2022082006-A1 BINDING ASSAYS INVOLVING A PLURALITY OF SYNTHETIC COMPOUNDS, TARGETS, AND COUNTER TARGETS SRI INTERNATIONAL (US) 2022-04-21 WO disclosed
US-20220106361-A1 MACROCYCLIC COMPOUNDS AND METHODS OF USE THEREOF GENENTECH, INC. (US) 2022-04-07 US disclosed
EP-3973990-A1 PROMOTOR FOR PERMEATION INTO CELL LAYER, COMPOSITION FOR FACILITATING DRUG AGENT ABSORPTION, AND PHARMACEUTICAL COMPOSITION University of Tsukuba (JP) 2022-03-30 EP disclosed
EP-3974563-A1 CYCLIC PEPTIDES Chugai Seiyaku Kabushiki Kaisha (JP) 2022-03-30 EP disclosed
WO-2022050529-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE ㈜베르티스 2022-03-10 WO disclosed
CN-111333697-B Synthesis method of romidepsin 深圳翰宇药业股份有限公司 2022-03-08 CN disclosed
CN-111333697-B Synthesis method of romidepsin 深圳翰宇药业股份有限公司 2022-03-08 CN disclosed
US-20220041547-A1 Compounds Useful for Treating a Mannheimia Haemolytica or Histophilus Somni Infection INTERVET INC. (US) 2022-02-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220106361-A1 MACROCYCLIC COMPOUNDS AND METHODS OF USE THEREOF PAICS, CYCS, LSS CASP3 53/4885KMT2A 2834/4885MDM4 1699/4885
US-20220041547-A1 Compounds Useful for Treating a Mannheimia Haemolytica or Histophilus Somni Infection SORD, HEXD, SNRPD1 CASP3 2283/4885KMT2A 2327/4885MDM4 2645/4885
US-12485182-B2 Proteoglycan mimetics for enhanced wound healing, angiogenesis, and vascular repair PDGFA, PDGFRB, TEK CASP3 809/4885KMT2A 4334/4885MDM4 4475/4885
US-11319347-B2 Peptide compound and method for producing same, composition for screening use, and method for selecting peptide compound VIP, NPPA, NGLY1 CASP3 2306/4885KMT2A 4395/4885MDM4 4154/4885
US-20260083852-A1 PROTEOGLYCAN MIMETICS FOR ENHANCED WOUND HEALING, ANGIOGENESIS, AND VASCULAR REPAIR PDGFA, DCLRE1A, PDGFRA CASP3 3953/4885KMT2A 2690/4885MDM4 3570/4885
US-20260001928-A1 CRF2 RECEPTOR AGONISTS AND THEIR USE IN THERAPY GIPR, NPY2R, NPY1R CASP3 4474/4885KMT2A 2458/4885MDM4 4186/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.