Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.55 |
| ▸ | FDPS | P14324 | 1/20 | 0.51 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.47 |
| ▸ | APP | P05067 | 2/20 | 0.46 |
| ▸ | BCHE | P06276 | 2/20 | 0.46 |
| ▸ | ACHE | P22303 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 9/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 9/20 | 0.46 |
| ▸ | CASP1 | P29466 | 8/20 | 0.46 |
| ▸ | CASP7 | P55210 | 8/20 | 0.46 |
| ▸ | USP2 | O75604 | 7/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.46 |
| ▸ | GLA | P06280 | 4/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CDK4 | P11802 | 1/20 | 0.45 |
| ▸ | CCND1 | P24385 | 1/20 | 0.45 |
| ▸ | CCND2 | P30279 | 1/20 | 0.45 |
| ▸ | CCND3 | P30281 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7683833 | 0.86 | FDPS (0.56) | PCSK9FDPSPDE10AAPPBCHE | |
| SCHEMBL27485928 | 0.83 | TLR8 (0.54) | PCSK9FDPSPDE10ABCHENPC1 | |
| SCHEMBL2578318 | 0.82 | FDPS (0.52) | PCSK9FDPSPDE10ABCHESMN1; SMN2 | |
| SCHEMBL27857084 | 0.80 | FDPS (0.51) | PCSK9FDPSPDE10ASMN1; SMN2 | |
| SCHEMBL27857097 | 0.80 | FDPS (0.51) | PCSK9FDPSPDE10ASMN1; SMN2 | |
| SCHEMBL27857007 | 0.80 | RAD52 (0.56) | PCSK9FDPSAPPBCHEACHE | |
| SCHEMBL3337103 | 0.80 | FDPS (0.53) | PCSK9FDPSPDE10AGAACYP2C19 | |
| SCHEMBL9271690 | 0.79 | FDPS (0.49) | PCSK9FDPSPDE10AALDH1A1HSD17B10 | |
| SCHEMBL30824524 | 0.79 | NCF1 (0.50) | PCSK9FDPSPDE10ABCHEACHE | |
| SCHEMBL2264548 | 0.79 | NCF1 (0.50) | PCSK9FDPSPDE10ABCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120118071-A | Quinazoline compound and application thereof | 北京化工大学 | 2025-06-10 | — | — | CN | claimed |
| CN-119751364-A | Dimethoxy quinazoline compound and application thereof | 中日友好医院(中日友好临床医学研究所) | 2025-04-04 | — | — | CN | claimed |
| CN-120118071-A | Quinazoline compound and application thereof | 北京化工大学 | 2025-06-10 | — | — | CN | disclosed |
| CN-119751364-A | Dimethoxy quinazoline compound and application thereof | 中日友好医院(中日友好临床医学研究所) | 2025-04-04 | — | — | CN | disclosed |
| CN-102491949-A | Method for synthesizing 2-(N-alkyl) aminopyrimidine derivatives by means of N-alkylation | UNIV NANJING SCIENCE & TECH | 2012-06-13 | — | — | CN | disclosed |