Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.50 |
| ▸ | DNM2 | P50570 | 2/20 | 0.49 |
| ▸ | FLT3 | P36888 | 6/20 | 0.48 |
| ▸ | TYRO3 | Q06418 | 6/20 | 0.48 |
| ▸ | MERTK | Q12866 | 6/20 | 0.48 |
| ▸ | GAS6 | Q14393 | 6/20 | 0.48 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.48 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.48 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.47 |
| ▸ | ELANE | P08246 | 2/20 | 0.46 |
| ▸ | TRIM58 | Q8NG06 | 1/20 | 0.46 |
| ▸ | AXL | P30530 | 3/20 | 0.45 |
| ▸ | CASP6 | P55212 | 1/20 | 0.44 |
| ▸ | GBA1 | P04062 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27857084 | 1.00 | FDPS (0.51) | FDPSNPSR1S1PR2LMNASMN1; SMN2 | |
| SCHEMBL2578318 | 0.98 | FDPS (0.52) | FDPSNPSR1S1PR2LMNASMN1; SMN2 | |
| SCHEMBL27485928 | 0.94 | TLR8 (0.54) | FDPSNPSR1KCNH3FLT3TYRO3 | |
| SCHEMBL7683833 | 0.87 | FDPS (0.56) | FDPSFLT3TYRO3MERTKGAS6 | |
| SCHEMBL11768489 | 0.84 | PCSK9 (0.44) | FDPSNPSR1S1PR2LMNASMN1; SMN2 | |
| SCHEMBL11477682 | 0.81 | FDPS (0.57) | FDPSKCNH3FLT3TYRO3MERTK | |
| SCHEMBL17653052 | 0.81 | TRIM58 (0.59) | KCNH3TYRO3MERTKTRIM58AXL | |
| SCHEMBL27857085 | 0.80 | PCSK9 (0.55) | FDPSSMN1; SMN2PCSK9PDE10A | |
| SCHEMBL27873802 | 0.79 | HPGD (0.59) | FDPSPCSK9PDE10AGBA1 | |
| SCHEMBL3337103 | 0.78 | FDPS (0.53) | FDPSDNM2PCSK9PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102491949-A | Method for synthesizing 2-(N-alkyl) aminopyrimidine derivatives by means of N-alkylation | UNIV NANJING SCIENCE & TECH | 2012-06-13 | — | — | CN | disclosed |