Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.35 |
| ▸ | MEN1 | O00255 | 6/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 7/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | CASP6 | P55212 | 1/20 | 0.33 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27843531 | 0.86 | BACE1 (0.32) | MAPTKDM4EHDAC1 | |
| SCHEMBL27843535 | 0.82 | ALDH1A1 (0.36) | NPC1RAB9AMAPTTP53KDM4E | |
| SCHEMBL27843541 | 0.80 | BRPF1 (0.35) | NPC1MEN1KMT2ARAB9AMAPT | |
| SCHEMBL27861060 | 0.80 | MCL1 (0.50) | NPC1MEN1KMT2ARAB9AMAPT | |
| SCHEMBL1025404 | 0.75 | KCNMA1 (0.53) | KMT2AKCNMA1RAB9APOLBTP53 | |
| SCHEMBL1023926 | 0.75 | JAK2 (0.40) | KCNMA1LMNAHTTGAA | |
| SCHEMBL27843595 | 0.73 | GRM4 (0.41) | NPC1KMT2ARAB9AKDM4EHTT | |
| SCHEMBL27843591 | 0.73 | KDM4E (0.41) | NPC1KMT2AKCNMA1RAB9AMAPT | |
| SCHEMBL27843688 | 0.72 | GRM4 (0.40) | NPC1KMT2AKCNMA1RAB9AKDM4E | |
| SCHEMBL27843600 | 0.71 | MEN1 (0.57) | MEN1KMT2AKCNMA1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102006776-B | Harmful arthropod control composition, and fused heterocyclic compound | SUMITOMO CHEMICAL CO | 2013-09-25 | — | — | CN | disclosed |
| CN-102006776-A | Harmful arthropod control composition, and fused heterocyclic compound | SUMITOMO CHEMICAL CO | 2011-04-06 | — | — | CN | disclosed |