Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.58 |
| ▸ | MEN1 | O00255 | 6/20 | 0.58 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | FDPS | P14324 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.44 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.44 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.43 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.43 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.43 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.43 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.43 |
| ▸ | CCR5 | P51681 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1377926 | 0.83 | FDPS (0.61) | KMT2AMEN1RXFP1KDM4ELMNA | |
| SCHEMBL15100730 | 0.76 | POLB (0.43) | KDM4EHPGDSMN1; SMN2TDP1NR4A1 | |
| SCHEMBL8174893 | 0.76 | PTGDR2 (0.49) | KMT2AMEN1KDM4ETDP1AKR1B1 | |
| SCHEMBL9127513 | 0.75 | MRGPRX4 (0.51) | KMT2AMEN1KDM4ESMN1; SMN2NR4A2 | |
| SCHEMBL31012122 | 0.74 | CYP1A2 (0.56) | KMT2AMEN1HPGDTDP1SLC1A3 | |
| SCHEMBL4850585 | 0.74 | CYP1A2 (0.56) | KMT2AMEN1HPGDTDP1SLC1A3 | |
| SCHEMBL12149845 | 0.74 | MEN1 (0.60) | KMT2AMEN1KDM4ELMNAHPGD | |
| Hydroxyamine SCHEMBL8924246 | 0.73 | MEN1 (0.53) | KMT2AMEN1HPGDTDP1SLC1A3 | |
| SCHEMBL1376902 | 0.73 | PARP10 (0.56) | KMT2AMEN1KDM4ELMNAFDPS | |
| SCHEMBL4795474 | 0.72 | TDP1 (0.61) | KMT2AMEN1KDM4ELMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102186803-A | Salicylic acid derivatives being farnesyl pyrophosphate synthase activity inhibitors | NOVARTIS AG | 2011-09-14 | — | — | CN | disclosed |