Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.56 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.56 |
| ▸ | FDPS | P14324 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.52 |
| ▸ | MEN1 | O00255 | 5/20 | 0.52 |
| ▸ | MAPK8 | P45983 | 3/20 | 0.51 |
| ▸ | MAPK9 | P45984 | 3/20 | 0.51 |
| ▸ | MAPK10 | P53779 | 3/20 | 0.51 |
| ▸ | CCR5 | P51681 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1377926 | 0.86 | FDPS (0.61) | PARP10PARP15FDPSKMT2AMEN1 | |
| SCHEMBL7910959 | 0.83 | PARP10 (0.64) | PARP10PARP15FDPSKMT2AMEN1 | |
| SCHEMBL7911237 | 0.81 | PARP10 (0.64) | PARP10PARP15FDPSKMT2AMEN1 | |
| SCHEMBL1375089 | 0.80 | PARP10 (0.61) | PARP10PARP15FDPSKMT2AMEN1 | |
| SCHEMBL14891403 | 0.80 | FFAR4 (0.54) | CCR5GAALMNA | |
| SCHEMBL18302008 | 0.77 | SLC6A3 (0.54) | KMT2AMEN1MAPK8MAPK9MAPK10 | |
| SCHEMBL12149845 | 0.76 | MEN1 (0.60) | PARP10PARP15FDPSKMT2AMEN1 | |
| SCHEMBL12149861 | 0.76 | PARP10 (0.67) | PARP10PARP15FDPSKMT2AMEN1 | |
| SCHEMBL16055509 | 0.75 | TDP1 (0.62) | KMT2AKDM4EGAALMNACYP3A4 | |
| SCHEMBL12149856 | 0.75 | PARP10 (0.60) | PARP10PARP15FDPSKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110288057-A1 | SALICYLIC ACID DERIVATIVES BEING FARNESYL PYROPHOSPHATE SYNTHASE ACTIVITY INHIBITORS | NOVARTIS AG (CH) | 2011-11-24 | — | — | US | disclosed |
| EP-2342173-A1 | SALICYLIC ACID DERIVATIVES BEING FARNESYL PYROPHOSPHATE SYNTHASE ACTIVITY INHIBITORS | Novartis AG (CH) | 2011-07-13 | — | — | EP | disclosed |
| WO-2010043584-A1 | SALICYLIC ACID DERIVATIVES BEING FARNESYL PYROPHOSPHATE SYNTHASE ACTIVITY INHIBITORS | NOVARTIS AG (CH) | 2010-04-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110288057-A1 | SALICYLIC ACID DERIVATIVES BEING FARNESYL PYROPHOSPHATE SYNTHASE ACTIVITY INHIBITORS | FDPS, GGPS1, COASY | PARP10 1018/4885PARP15 521/4885FDPS 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.