Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 10/20 | 0.47 |
| ▸ | MEN1 | O00255 | 9/20 | 0.47 |
| ▸ | MAPT | P10636 | 8/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | CDK4 | P11802 | 2/20 | 0.45 |
| ▸ | CCND1 | P24385 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CDK2 | P24941 | 1/20 | 0.44 |
| ▸ | MC5R | P33032 | 2/20 | 0.44 |
| ▸ | MC3R | P41968 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MC4R | P32245 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2788223 | 0.91 | MEN1 (0.46) | KMT2AMEN1MAPTTDP1KDM4E | |
| SCHEMBL9943267 | 0.89 | MC5R (0.49) | KMT2AMEN1MAPTCDK4CCND1 | |
| SCHEMBL2788511 | 0.87 | CDK4 (0.48) | KMT2AMEN1MAPTTDP1KDM4E | |
| SCHEMBL2787710 | 0.85 | KMT2A (0.52) | KMT2AMEN1MAPTTDP1KDM4E | |
| SCHEMBL2789631 | 0.83 | KMT2A (0.53) | KMT2AMEN1MAPTPOLB | |
| SCHEMBL9943315 | 0.82 | GOT1 (0.44) | KMT2AMEN1MAPTCDK4CCND1 | |
| SCHEMBL9943439 | 0.82 | MC5R (0.47) | KMT2AMEN1MAPTCDK4CCND1 | |
| SCHEMBL9943282 | 0.82 | MC5R (0.47) | KMT2AMEN1MAPTCDK4CCND1 | |
| SCHEMBL2787985 | 0.81 | MC5R (0.43) | KMT2AMEN1MAPTCDK4CCND1 | |
| SCHEMBL9943323 | 0.81 | GOT1 (0.44) | KMT2AMEN1MAPTCDK4CCND1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8227502-B2 | Amides acting on the adenosine receptors | ANAMAR AB (SE) | 2012-07-24 | — | — | US | claimed |
| EP-2099815-B1 | NOVEL AMIDES ACTING ON THE ADENOSINE RECEPTORS | ANAMAR AB (SE) | 2012-06-20 | — | — | EP | claimed |
| US-8227502-B2 | Amides acting on the adenosine receptors | ANAMAR AB (SE) | 2012-07-24 | — | — | US | disclosed |
| EP-2099815-B1 | NOVEL AMIDES ACTING ON THE ADENOSINE RECEPTORS | ANAMAR AB (SE) | 2012-06-20 | — | — | EP | disclosed |
| US-20100098629-A1 | Novel Amides Acting on the Adenosine Receptors | ACURE PHARMA AB (SE) | 2010-04-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100098629-A1 | Novel Amides Acting on the Adenosine Receptors | ADORA1, ADORA3, ADORA2B | KMT2A 3804/4885MEN1 4664/4885MAPT 4617/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.