Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | AURKA | O14965 | 1/20 | 0.45 |
| ▸ | MTOR | P42345 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.41 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.41 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2172048 | 1.00 | ALDH1A1 (0.47) | ALDH1A1MAPTSMN1; SMN2LMNATP53 | |
| SCHEMBL2172237 | 0.92 | AURKA (0.43) | ALDH1A1MAPTSMN1; SMN2LMNATP53 | |
| SCHEMBL2786112 | 0.92 | AURKA (0.43) | ALDH1A1MAPTSMN1; SMN2LMNATP53 | |
| SCHEMBL1672882 | 0.91 | BCL2 (0.45) | ALDH1A1MAPTSMN1; SMN2LMNAKMT2A | |
| SCHEMBL1614322 | 0.90 | MAPT (0.47) | ALDH1A1MAPTSMN1; SMN2LMNAKMT2A | |
| SCHEMBL1614599 | 0.89 | AURKA (0.50) | ALDH1A1MAPTLMNAKMT2AAURKA | |
| SCHEMBL1670279 | 0.89 | AURKA (0.50) | ALDH1A1MAPTLMNAKMT2AAURKA | |
| SCHEMBL2785877 | 0.89 | MEN1 (0.43) | ALDH1A1MAPTSMN1; SMN2LMNATP53 | |
| SCHEMBL2785875 | 0.89 | MEN1 (0.43) | ALDH1A1MAPTSMN1; SMN2LMNATP53 | |
| SCHEMBL2785880 | 0.89 | MEN1 (0.43) | ALDH1A1MAPTSMN1; SMN2LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2254576-A1 | ANDROGEN RECEPTOT-ABLATIVE AGENTS | The Ohio State University Research Foundation (US) | 2010-12-01 | — | — | EP | claimed |
| WO-2009105621-A1 | ANDROGEN RECEPTOT-ABLATIVE AGENTS | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2009-08-27 | — | — | WO | claimed |