Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 10/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | UBE2N | P61088 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | FABP4 | P15090 | 1/20 | 0.31 |
| ▸ | MET | P08581 | 1/20 | 0.31 |
| ▸ | KRAS | P01116 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.30 |
| ▸ | BCHE | P06276 | 1/20 | 0.30 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28750987 | 0.80 | HTT (0.46) | HTR6KDM4EUBE2NKMT2AFABP4 | |
| SCHEMBL27558868 | 0.75 | KDM4E (0.60) | HTR6KDM4EUBE2NKMT2AL3MBTL1 | |
| SCHEMBL27880179 | 0.75 | KDM4E (0.41) | HTR6KDM4EUBE2NL3MBTL1CYP19A1 | |
| SCHEMBL4560894 | 0.74 | HTR6 (0.56) | HTR6KDM4EUBE2NKMT2AL3MBTL1 | |
| SCHEMBL27771343 | 0.74 | HDAC3 (0.35) | HTR6FABP4 | |
| SCHEMBL28777481 | 0.73 | HDAC3 (0.35) | HTR6 | |
| SCHEMBL28777651 | 0.73 | HTR6 (0.34) | HTR6 | |
| SCHEMBL27572608 | 0.72 | CA1 (0.46) | CYP19A1 | |
| SCHEMBL27879774 | 0.71 | HTR6 (0.36) | HTR6KMT2AFABP4L3MBTL1 | |
| SCHEMBL27678077 | 0.71 | FABP4 (0.38) | HTR6FABP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102574836-A | Aminopyrazole Derivatives | CHUGAI PHARMACEUTICAL CO LTD | 2012-07-11 | — | — | CN | disclosed |