Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 6/20 | 0.36 |
| ▸ | FABP4 | P15090 | 4/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.32 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.32 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.32 |
| ▸ | RAPGEF4 | Q8WZA2 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27799540 | 0.86 | FABP4 (0.38) | HTR6FABP4HTTMEN1KMT2A | |
| SCHEMBL28750987 | 0.83 | HTT (0.46) | HTR6FABP4HTTMEN1KMT2A | |
| SCHEMBL28946823 | 0.79 | HTR6 (0.53) | HTR6 | |
| SCHEMBL27678077 | 0.79 | FABP4 (0.38) | HTR6FABP4HTTRAPGEF4MAPT | |
| SCHEMBL28799515 | 0.78 | HTR6 (0.35) | HTR6SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL29408218 | 0.74 | MEN1 (0.60) | HTR6FABP4HTTMEN1KMT2A | |
| SCHEMBL2573218 | 0.74 | MEN1 (0.60) | HTR6FABP4HTTMEN1KMT2A | |
| SCHEMBL27634824 | 0.73 | PPARG (0.43) | FABP4RAPGEF4TDP1HDAC3HDAC4 | |
| SCHEMBL27677914 | 0.73 | HTR6 (0.42) | HTR6HTTMEN1KMT2APKM | |
| SCHEMBL27863452 | 0.71 | NOTUM (0.37) | HTR6FABP4KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102933557-A | Radioprotector compounds and methods | PETER MACCALLUM CANCER INST | 2013-02-13 | — | — | CN | disclosed |
| CN-102803250-A | 1, 3-disubstituted imidazolidin-2-one derivatives as inhibitors of CYP17 | NOVARTIS AG | 2012-11-28 | — | — | CN | disclosed |
| CN-102574836-A | Aminopyrazole Derivatives | CHUGAI PHARMACEUTICAL CO LTD | 2012-07-11 | — | — | CN | disclosed |