Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Propylene Glycol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 3/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.30 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.30 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propylene Glycol SCHEMBL8520043 | 0.95 | TDP1 (0.46) | TDP1CA1CA2CA7CA9 | |
| Propylene Glycol SCHEMBL20740683 | 0.89 | TDP1 (0.40) | TDP1CA1CA2CA7CA9 | |
| Propylene Glycol SCHEMBL27763183 | 0.89 | TDP1 (0.40) | TDP1CA1CA2CA7CA9 | |
| Propylene Glycol SCHEMBL243616 | 0.89 | TDP1 (0.40) | TDP1CA1CA2CA7CA9 | |
| Isobutanol SCHEMBL28172126 | 0.87 | TSHR (0.47) | TDP1CA1CA2CA7CA9 | |
| Isopropyl Alcohol SCHEMBL8520886 | 0.87 | CA1 (0.50) | TDP1CA1CA2CA7CA9 | |
| Propylene Glycol SCHEMBL460713 | 0.86 | TDP1 (0.37) | TDP1CA1CA2CA7MEN1 | |
| Methacrylic Acid SCHEMBL5050934 | 0.84 | TDP1 (0.36) | TDP1CA1CA2CA7TSHR | |
| 1-Pentanol SCHEMBL28108023 | 0.84 | SMN1; SMN2 (0.43) | TDP1CA1CA2CA7MEN1 | |
| 1,3-Butanediol SCHEMBL5927899 | 0.84 | CA1 (0.41) | TDP1CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 4251 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240278210-A1 | PREPARATION METHOD OF SUPER ABSORBENT POLYMER AND SUPER ABSORBENT POLYMER | LG CHEM, LTD. (KR) | 2024-08-22 | — | — | US | claimed |
| US-20240182733-A1 | INKJET INK, INK SET, INK MEDIUM SET, AND PRINTING MEDIUM | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2024-06-06 | — | — | US | claimed |
| CN-116063614-B | Anti-swelling and shrinkage swelling agent and preparation method and application thereof | 中国石油化工股份有限公司 | 2024-05-07 | — | — | CN | claimed |
| CN-116063625-B | Anti-swelling and shrinkage swelling agent, and preparation method and application thereof | 中国石油化工股份有限公司 | 2024-05-07 | — | — | CN | claimed |
| CN-116064016-B | Scale inhibition anti-swelling shrinkage swelling agent and preparation method and application thereof | 中国石油化工股份有限公司 | 2024-04-05 | — | — | CN | claimed |
| CN-109462985-B | Aqueous alkaline binder component which is hardened by means of carbon dioxide gas | 胡坦斯·阿尔伯图斯化学厂有限公司 | 2024-03-19 | — | — | CN | claimed |
| EP-4328032-A1 | INKJET INK, INK SET, INK MEDIUM SET, AND PRINTING MEDIUM | Nippon Kayaku Kabushiki Kaisha (JP) | 2024-02-28 | — | — | EP | claimed |
| EP-4321561-A1 | PREPARATION METHOD OF SUPER ABSORBENT POLYMER AND SUPER ABSORBENT POLYMER | LG Chem, Ltd. (KR) | 2024-02-14 | — | — | EP | claimed |
| CN-117321120-A | Method for producing superabsorbent polymer and superabsorbent polymer | 株式会社LG化学 | 2023-12-29 | — | — | CN | claimed |
| CN-117120556-A | Ink for inkjet, ink set, ink medium set, and printing medium | 日本化药株式会社 | 2023-11-24 | — | — | CN | claimed |
| WO-1991009923-A1 | ULTRA MILD SURFACTANT WITH FOAM ENHANCER . | THE PROCTER & GAMBLE COMPANY (US) | 1991-07-11 | — | — | WO | claimed |
| EP-0220645-B1 | PHOTOSENSITIVE POSITIVE COMPOSITION AND PHOTORESIST MATERIAL PREPARED THEREWITH | HOECHST CELANESE CORPORATION (US) | 1990-09-12 | — | — | EP | claimed |
| US-4948697-A | IMPROVED ODOR AND INCREASED PHTOSPEED | HOECHST CELANESE CORPORATION (US) | 1990-08-14 | — | — | US | claimed |
| EP-0221428-B1 | LIQUID FOR THE TREATMENT OF A PHOTORESIST COMPOSITION, AND PROCESS THEREFOR | HOECHST CELANESE CORPORATION (US) | 1989-11-23 | — | — | EP | claimed |
| US-4808235-A | SPRAYING BLADES WITH MIXTURES OF GLYCOL ETHERS, ADD WCTS OR POLYETHERS; ON-LINE | THE DOW CHEMICAL COMPANY (US) | 1989-02-28 | — | — | US | claimed |
| EP-0275987-A2 | Composition and method for cleaning gas turbine compressors | THE DOW CHEMICAL COMPANY (US) | 1988-07-27 | — | — | EP | claimed |
| US-4670171-A | MIXTURE OF PHOSPHATE SEQUESTERING AGENT, WETTING AGENT, SURFACTANTS, AND FOAMING AGENTS | PENNZOIL COMPANY (US) | 1987-06-02 | — | — | US | claimed |
| EP-0051483-B1 | STABLE AQUEOUS EPOXY DISPERSIONS | CELANESE CORPORATION (US) | 1985-01-16 | — | — | EP | claimed |
| EP-0051483-A1 | Stable aqueous epoxy dispersions | CELANESE CORPORATION (US) | 1982-05-12 | — | — | EP | claimed |
| US-4315044-A | DIGLYCIDYL ETHERS OF IDHYDRIC PHENOL AND POLYOXY-ALKLENE GLYCOL, WATERBASE PAINTS | CELANESE CORPORATION (US) | 1982-02-09 | — | — | US | claimed |