Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Propylene Glycol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propylene Glycol SCHEMBL278652 | 0.95 | TDP1 (0.50) | TDP1CA1CA2CA7MEN1 | |
| Propylene Glycol SCHEMBL460713 | 0.86 | TDP1 (0.37) | TDP1CA1CA2CA7MEN1 | |
| Propylene Glycol SCHEMBL20740683 | 0.85 | TDP1 (0.40) | TDP1CA1CA2CA7MEN1 | |
| Propylene Glycol SCHEMBL243616 | 0.85 | TDP1 (0.40) | TDP1CA1CA2CA7MEN1 | |
| Propylene Glycol SCHEMBL27763183 | 0.85 | TDP1 (0.40) | TDP1CA1CA2CA7MEN1 | |
| Alcohol SCHEMBL45595 | 0.85 | MEN1 (0.46) | TDP1CA1CA2CA7MEN1 | |
| 1-Pentanol SCHEMBL28108023 | 0.85 | SMN1; SMN2 (0.43) | TDP1CA1CA2CA7MEN1 | |
| Isobutanol SCHEMBL28172126 | 0.83 | TSHR (0.47) | TDP1CA1CA2CA7MEN1 | |
| Isopropyl Alcohol SCHEMBL8520886 | 0.83 | CA1 (0.50) | TDP1CA1CA2CA7MEN1 | |
| Propylene Glycol SCHEMBL998699 | 0.82 | TSHR (0.42) | TDP1CA1CA2CA7MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-11158005-A | — | — | None | — | — | JP | disclosed |
| CN-114269892-B | Composition and method for cleaning adhesive polymer | 株式会社力森诺科 | 2024-02-23 | — | — | CN | disclosed |
| CN-115427547-A | Composition and method for cleaning adhesive polymer | 昭和电工株式会社 | 2022-12-02 | — | — | CN | disclosed |
| CN-114269892-A | Composition and method for cleaning adhesive polymer | 昭和电工株式会社 | 2022-04-01 | — | — | CN | disclosed |
| WO-2021039274-A1 | COMPOSITION, AND METHOD FOR CLEANING ADHESIVE POLYMER | 昭和電工株式会社 | 2021-03-04 | — | — | WO | disclosed |
| JP-H11158005-A | METHOD FOR DECREASING ADSORPTION OF FUNGICIDAL AND MILDEWPROOFING AGENT | PIGEON CORP | 1999-06-15 | — | — | JP | disclosed |