Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K1 | Q92918 | 10/20 | 0.52 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.44 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.44 |
| ▸ | PIM1 | P11309 | 1/20 | 0.43 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.43 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27882090 | 0.90 | MAP4K1 (0.54) | MAP4K1PIK3CAMAPTNPC1RAB9A | |
| SCHEMBL12812402 | 0.89 | PIM1 (0.52) | MAP4K1PIK3CAMAPTNPC1RAB9A | |
| SCHEMBL12812447 | 0.85 | PTPN11 (0.46) | MAP4K1PIK3CAMAPTNPC1RAB9A | |
| SCHEMBL1442090 | 0.84 | PDGFRB (0.51) | PIK3CAMAPTNPC1RAB9AALDH1A1 | |
| SCHEMBL27865822 | 0.84 | PIK3CA (0.48) | MAP4K1PIK3CAMAPTNPC1RAB9A | |
| SCHEMBL27865655 | 0.83 | MAPT (0.44) | MAP4K1PIK3CAMAPTNPC1RAB9A | |
| SCHEMBL27882148 | 0.83 | PIK3CA (0.51) | PIK3CAMAPTNPC1RAB9AALDH1A1 | |
| SCHEMBL1442139 | 0.82 | ALDH1A1 (0.47) | PIK3CAMAPTNPC1RAB9AALDH1A1 | |
| SCHEMBL1442175 | 0.82 | PIK3CA (0.50) | PIK3CAMAPTNPC1RAB9AALDH1A1 | |
| SCHEMBL1442693 | 0.82 | HCRTR2 (0.45) | PIK3CAMAPTNPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102596932-A | Substituted aminoquinoxalines as tyrosine threonine kinase inhibitors | BAYER SCHERING PHARMA AG | 2012-07-18 | — | — | CN | claimed |