SCHEMBL27866331

SCHEMBL27866331

CO[Si](CC(c1ccccc1)C(C)Br)(OC)OC

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 4/20 0.41
KCNA5 P22460 6/20 0.37
PKM P14618 1/20 0.35
HTR2A P28223 2/20 0.33
HRH1 P35367 2/20 0.33
LMNA P02545 2/20 0.33
SLC6A2 P23975 2/20 0.33
SLC6A4 P31645 2/20 0.33
SLC6A3 Q01959 2/20 0.33
TRPA1 O75762 1/20 0.33
KCNA3 P22001 1/20 0.33
CYP1A2 P05177 1/20 0.33
CHRM2 P08172 1/20 0.33
CHRM4 P08173 1/20 0.33
CHRM5 P08912 1/20 0.33
ADRA2A P08913 1/20 0.33
CYP2D6 P10635 1/20 0.33
CHRM1 P11229 1/20 0.33
TSHR P16473 1/20 0.33
ADRA2B P18089 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27791294 0.84 TAAR1 (0.40) TAAR1KCNA5PKMHTR2AHRH1
SCHEMBL27866327 0.82 TAAR1 (0.39) TAAR1HTR2AHRH1LMNASLC6A2
SCHEMBL27791214 0.82 HKDC1 (0.38) TAAR1KCNA5PKMHTR2AHRH1
SCHEMBL8374293 0.79 TAAR1 (0.48) TAAR1TRPA1
SCHEMBL18662217 0.78 HRH1 (0.41) TAAR1HTR2AHRH1LMNASLC6A2
SCHEMBL27791407 0.77 HKDC1 (0.37) TAAR1KCNA5HTR2AHRH1LMNA
SCHEMBL28330761 0.73 SLC6A4 (0.36) TAAR1HTR2AHRH1LMNASLC6A2
SCHEMBL1765956 0.73 LMNA (0.52) LMNACYP1A2CYP2D6TSHRKDM4E
SCHEMBL28198312 0.73 SCN4A (0.46)
SCHEMBL10831868 0.71 HKDC1 (0.52) TAAR1PKMHTR2ALMNASLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102432924-A Rubber composition, method of making the same, and articles made therefrom MOMENTIVE PERFORMANCE MAT INC 2012-05-02 CN disclosed