SCHEMBL2786641

SCHEMBL2786641

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nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.43
CTH P32929 1/20 0.43
CBS P35520 1/20 0.43
THPO P40225 1/20 0.43
THRB P10828 1/20 0.41
LMNA P02545 2/20 0.36
MEN1 O00255 1/20 0.36
HPGD P15428 1/20 0.36
BLM P54132 1/20 0.36
KMT2A Q03164 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
ALDH1A1 P00352 1/20 0.35
TPI1 P60174 1/20 0.33
ALOX15 P16050 1/20 0.33
PGK1 P00558 1/20 0.32
PGK2 P07205 1/20 0.32
CYP3A4 P08684 1/20 0.32
SLC22A6 Q4U2R8 1/20 0.32
LDHA P00338 1/20 0.32
SRR Q9GZT4 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10476512 0.84 TSHR (0.36) TSHRCTHCBSTHPOTHRB
Phosphoglycolic Acid SCHEMBL380471 0.79
SCHEMBL8852887 0.79 MVD (0.42) TSHRCTHCBSTHPOTHRB
Phosphoglycolic Acid SCHEMBL20798069 0.79 TPI1 (0.54) TSHRCTHCBSTHPOTHRB
SCHEMBL2984826 0.78 SMN1; SMN2 (0.32) TSHRCTHCBSTHPOTHRB
SCHEMBL20712038 0.77 TSHR (0.58) TSHRLMNAKMT2ATDP1ALDH1A1
Phosphoglycolic Acid SCHEMBL5586781 0.77 TPI1 (0.52) TSHRCTHCBSTHPOTHRB
Phosphoglycolic Acid SCHEMBL29156120 0.77 TPI1 (0.52) TSHRCTHCBSTHPOTHRB
SCHEMBL13022683 0.77
Phosphoglycolic Acid SCHEMBL27790872 0.77 TSHR (0.39) TSHRCTHCBSTHPOTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116077642-A Compositions and methods for reducing or preventing metastasis 高级健康研究所 2023-05-09 CN disclosed
CN-109310773-B Formulations containing TLR agonists and methods of use 传染病研究所 2022-04-26 CN disclosed
CN-107540730-B Vaccines for HSV-2 免疫设计公司 2021-07-16 CN disclosed
CN-107540730-A Vaccine for HSV 2 免疫设计公司 2018-01-05 CN disclosed
CN-104412108-B Vaccines for HSV-2 免疫设计公司 2017-08-25 CN disclosed
US-9480740-B2 Synthetic glucopyranosyl lipid adjuvants INFECTIOUS DISEASE RESEARCH INSTITUTE (US) 2016-11-01 US disclosed
US-20140322268-A1 SYNTHETIC GLUCOPYRANOSYL LIPID ADJUVANTS INFECTIOUS DISEASE RESEARCH INSTITUTE (US) 2014-10-30 US disclosed
CN-102965959-B Wool refining treating fluid and treating method UNIV TIANJIN POLYTECHNIC 2014-05-28 CN disclosed
CN-102965959-A Wool refining treating fluid and treating method UNIV TIANJIN POLYTECHNIC 2013-03-13 CN disclosed
US-20100310602-A1 SYNTHETIC GLUCOPYRANOSYL LIPID ADJUVANTS INFECTIOUS DISEASE RESEARCH INSTITUTE (US) 2010-12-09 US disclosed
US-5384241-A Specific binding assay compound with inhibitive self-quenching characteristics ENZO DIAGNOSTICS, INC. (US) 1995-01-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140322268-A1 SYNTHETIC GLUCOPYRANOSYL LIPID ADJUVANTS B3GAT3, GLA, LGALS8 TSHR 1791/4885CTH 4361/4885CBS 4489/4885
US-20100310602-A1 SYNTHETIC GLUCOPYRANOSYL LIPID ADJUVANTS B3GAT3, GLA, LGALS8 TSHR 1791/4885CTH 4361/4885CBS 4489/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.