Sugi Predict

Sugi Predict / Compounds / SCHEMBL278677

SCHEMBL278677

SCHEMBL278677

C=CCN(CC=C)OC(=O)c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TSHR P16473 2/20 0.46
▸ LMNA P02545 4/20 0.45
▸ F2 P00734 1/20 0.45
▸ RAB9A P51151 1/20 0.45
▸ KMT2A Q03164 4/20 0.43
▸ TDP1 Q9NUW8 3/20 0.43
▸ MEN1 O00255 2/20 0.43
▸ SMN1; SMN2 Q16637 2/20 0.43
▸ KDM4E B2RXH2 1/20 0.43
▸ AKT1 P31749 1/20 0.42
▸ MAPK1 P28482 1/20 0.42
▸ HIF1A Q16665 1/20 0.42
▸ SLC6A2 P23975 1/20 0.42
▸ SLC6A3 Q01959 1/20 0.42
▸ CYP3A4 P08684 2/20 0.41
▸ L3MBTL1 Q9Y468 1/20 0.41
▸ LSS P48449 2/20 0.41
▸ ALDH1A1 P00352 3/20 0.41
▸ MAPT P10636 1/20 0.41
▸ HPGD P15428 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7152785 0.84 LSS (0.44) TSHRLMNARAB9AKMT2ATDP1
SCHEMBL29395313 0.83 TSHR (0.47) TSHRLMNAF2RAB9AKMT2A
SCHEMBL7200651 0.80 RAB9A (0.44) TSHRLMNAF2RAB9AKMT2A
SCHEMBL1395532 0.76 TDP1 (0.49) TSHRLMNAF2RAB9AKMT2A
SCHEMBL9329275 0.76 TSHR (0.53) TSHRLMNAF2RAB9AKMT2A
SCHEMBL11567916 0.76 CYP3A4 (0.42) TSHRLMNARAB9AKMT2ATDP1
SCHEMBL28406786 0.76 LMNA (0.50) TSHRLMNAF2KMT2ATDP1
SCHEMBL1730081 0.76 LMNA (0.53) TSHRLMNAF2RAB9AKMT2A
SCHEMBL28420204 0.75 TDP1 (0.46) LMNAF2KMT2ATDP1MEN1
SCHEMBL16756573 0.74 LMNA (0.54) TSHRLMNAF2RAB9AKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240141078-A1 AMINE CO-INITIATOR MIXTURE ARKEMA FRANCE (FR) 2024-05-02 — — US claimed
US-20050244752-A1 Radiation-curable resin composition for adhesives JSR CORPORATION (JP) 2005-11-03 — — US claimed
EP-1487932-A2 RADIATION-CURABLE RESIN COMPOSITION FOR ADHESIVES DSM IP Assets B.V. (NL) 2004-12-22 — — EP claimed
WO-2003080755-A2 RADIATION-CURABLE RESIN COMPOSITION FOR ADHESIVES DSM IP ASSETS B.V. (NL) 2003-10-02 — — WO claimed
US-12084456-B2 Isocarbostyril alkaloids and functionalization thereof THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2024-09-10 — — US disclosed
US-20240141078-A1 AMINE CO-INITIATOR MIXTURE ARKEMA FRANCE (FR) 2024-05-02 — — US disclosed
US-20220064176-A1 ISOCARBOSTYRIL ALKALOIDS AND FUNCTIONALIZATION THEREOF THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2022-03-03 — — US disclosed
US-10457693-B2 Organoboron compounds and methods of making organoboron compounds THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2019-10-29 — — US disclosed
EP-3511747-A1 LIGHT-DIFFUSING FILM AND PRODUCTION METHOD THEREFOR, AND DISPLAY DEVICE Daicel Corporation (JP) 2019-07-17 — — EP disclosed
US-20190176434-A1 LIGHT-DIFFUSING FILM AND PRODUCTION METHOD THEREFOR, AND DISPLAY DEVICE DAICEL CORPORATION (JP) 2019-06-13 — — US disclosed
US-20190031688-A1 ORGANOBORON COMPOUNDS AND METHODS OF MAKING ORGANOBORON COMPOUNDS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2019-01-31 — — US disclosed
US-10183957-B2 Organoboron compounds and methods of making organoboron compounds THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2019-01-22 — — US disclosed
WO-2003080755-A2 RADIATION-CURABLE RESIN COMPOSITION FOR ADHESIVES DSM IP ASSETS B.V. (NL) 2003-10-02 — — WO disclosed
US-20020135714-A1 Optical diffusion element and display device equipped with the optical diffusion element FUJIFILM CORPORATION (JP) 2002-09-26 — — US disclosed
EP-1107336-A2 Nonaqueous electrolyte battery SONY CORPORATION (JP) 2001-06-13 — — EP disclosed
EP-0618244-B1 Multiple curable composition and use thereof NAT STARCH CHEM INVEST (US) 1998-07-15 — — EP disclosed
EP-0618244-A2 Multiple curable composition and use thereof W.R. GRACE & CO.-CONN. (US) 1994-10-05 — — EP disclosed
EP-0314623-B1 SUBSTITUTED HYDROXYLAMINE ESTER STABILIZERS CIBA-GEIGY AG (CH) 1993-08-04 — — EP disclosed
US-4894314-A FOR POLYMERIZATION BY EXPOSURE TO VISIBLE LASER LIGHT MORTON THIOKOL, INC. (US) 1990-01-16 — — US disclosed
EP-0314623-A2 Substituted hydroxylamine ester stabilizers CIBA-GEIGY AG (CH) 1989-05-03 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220064176-A1 ISOCARBOSTYRIL ALKALOIDS AND FUNCTIONALIZATION THEREOF NISCH, CIAPIN1, CA7 TSHR 3739/4885LMNA 2617/4885F2 4439/4885
US-12084456-B2 Isocarbostyril alkaloids and functionalization thereof NISCH, CIAPIN1, CA7 TSHR 3739/4885LMNA 2617/4885F2 4439/4885
US-20240141078-A1 AMINE CO-INITIATOR MIXTURE JMJD6, KDM2B, KDM1B TSHR 4410/4885LMNA 968/4885F2 755/4885
US-10457693-B2 Organoboron compounds and methods of making organoboron compounds NDC1, ELOC, UGT2B7 TSHR 4538/4885LMNA 1125/4885F2 3456/4885
US-10183957-B2 Organoboron compounds and methods of making organoboron compounds NDC1, ELOC, UGT2B7 TSHR 4538/4885LMNA 1125/4885F2 3456/4885
US-20190031688-A1 ORGANOBORON COMPOUNDS AND METHODS OF MAKING ORGANOBORON COMPOUNDS NDC1, ELOC, UGT2B7 TSHR 4538/4885LMNA 1125/4885F2 3456/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.