Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.39 |
| ▸ | P2RX3 | P56373 | 6/20 | 0.39 |
| ▸ | PLA2G4A | P47712 | 7/20 | 0.37 |
| ▸ | PPARG | P37231 | 3/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.36 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 2/20 | 0.35 |
| ▸ | PPARA | Q07869 | 2/20 | 0.35 |
| ▸ | ACLY | P53396 | 1/20 | 0.35 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27884356 | 0.86 | PPARG (0.43) | PLA2G4APPARGPPARDPPARAACLY | |
| SCHEMBL28800052 | 0.85 | ACLY (0.43) | PLA2G4APPARGPPARDPPARAACLY | |
| SCHEMBL12096769 | 0.83 | PPARG (0.47) | ADRB1ADRB3P2RX3PPARGPPARD | |
| SCHEMBL28797216 | 0.83 | PHGDH (0.41) | PLA2G4APPARGPPARDPPARAACLY | |
| SCHEMBL27884365 | 0.82 | ACLY (0.40) | PLA2G4APPARGPPARDPPARAACLY | |
| SCHEMBL27867768 | 0.81 | P2RX3 (0.39) | ADRB1ADRB3P2RX3PLA2G4APPARG | |
| SCHEMBL27867735 | 0.80 | ACLY (0.42) | PLA2G4APPARGPPARDPPARAACLY | |
| SCHEMBL27884472 | 0.80 | PHGDH (0.39) | PLA2G4APPARGPPARDPPARAACLY | |
| SCHEMBL27867729 | 0.80 | ACLY (0.38) | PLA2G4APPARGPPARDPPARAACLY | |
| SCHEMBL27867759 | 0.80 | ACLY (0.38) | PLA2G4APPARGPPARDPPARAACLY |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102596906-A | Use of indole derivatives as NURR-1 activators as agents for the treatment of Parkinson's disease | FOURNIER LAB SA | 2012-07-18 | — | — | CN | disclosed |