Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RHOC | P08134 | 1/20 | 0.41 |
| ▸ | RHOA | P61586 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 6/20 | 0.39 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 5/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.39 |
| ▸ | RELA | Q04206 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1198654 | 0.83 | ALDH1A1 (0.57) | SMN1; SMN2RAB9ANPC1MAPTTSHR | |
| SCHEMBL27636079 | 0.82 | POLB (0.53) | SMN1; SMN2POLBRAB9ANPC1MAPT | |
| SCHEMBL627613 | 0.82 | LMNA (0.45) | RHOCRHOAPOLBMAPTLMNA | |
| SCHEMBL628071 | 0.81 | LMNA (0.53) | RHOCRHOASMN1; SMN2POLBLMNA | |
| SCHEMBL27657106 | 0.80 | TP53 (0.51) | SMN1; SMN2POLBRAB9ANPC1MAPT | |
| Lithium Ion SCHEMBL27657107 | 0.79 | TP53 (0.50) | SMN1; SMN2POLBRAB9ANPC1MAPT | |
| SCHEMBL13148445 | 0.76 | LMNA (0.43) | RHOCRHOASMN1; SMN2POLBLMNA | |
| SCHEMBL628077 | 0.72 | RHOC (0.50) | RHOCRHOAPOLBMAPTLMNA | |
| SCHEMBL627651 | 0.71 | LMNA (0.59) | RHOCRHOASMN1; SMN2POLBLMNA | |
| SCHEMBL18724389 | 0.71 | DYRK1A (0.42) | RAB9ANPC1MAPTLMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102459203-A | Compositions and methods for modulating retinol binding to retinol binding protein 4(RBP4) | IRM LLC | 2012-05-16 | — | — | CN | disclosed |