Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27869291 | 0.96 | ALDH1A1 (0.45) | ALDH1A1HSD17B10HPGDNPSR1KMT2A | |
| SCHEMBL30682981 | 0.83 | MMP13 (0.44) | ALDH1A1KMT2ANPC1RAB9AKDM4E | |
| SCHEMBL143705 | 0.79 | GAA (0.50) | ALDH1A1NPSR1KMT2ARAB9AGAA | |
| Ammonia Solution, Strong SCHEMBL5917791 | 0.77 | GAA (0.48) | ALDH1A1NPSR1KMT2ARAB9AGAA | |
| SCHEMBL19949926 | 0.77 | GAA (0.48) | ALDH1A1NPSR1KMT2ARAB9AGAA | |
| SCHEMBL28693175 | 0.76 | ALDH1A1 (0.56) | ALDH1A1HSD17B10HPGDNPSR1KMT2A | |
| SCHEMBL10880217 | 0.75 | GAA (0.42) | ALDH1A1KMT2ANPC1RAB9AGAA | |
| SCHEMBL15940656 | 0.74 | CYP2D6 (0.61) | ALDH1A1HSD17B10HPGDNPSR1KMT2A | |
| SCHEMBL28693176 | 0.73 | ALDH1A1 (0.54) | ALDH1A1HSD17B10HPGDNPSR1KMT2A | |
| Threonine SCHEMBL28509117 | 0.72 | SLC1A3 (0.49) | ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102395584-A | Compounds for the treatment of metabolic disorders | PROSIDION LTD | 2012-03-28 | — | — | CN | disclosed |