Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31633655 | 0.98 | ALDH1A1 (0.51) | ALDH1A1HSD17B10HPGDNPSR1KMT2A | |
| SCHEMBL28693175 | 0.85 | ALDH1A1 (0.56) | ALDH1A1HSD17B10HPGDNPSR1KMT2A | |
| SCHEMBL16759629 | 0.80 | ALDH1A1 (0.55) | ALDH1A1HSD17B10HPGDNPSR1KMT2A | |
| SCHEMBL22118707 | 0.78 | ALDH1A1 (0.52) | ALDH1A1HSD17B10HPGDNPSR1KMT2A | |
| SCHEMBL25418263 | 0.75 | KMT2A (0.51) | ALDH1A1HSD17B10HPGDNPSR1KMT2A | |
| SCHEMBL5550702 | 0.74 | ALDH1A1 (0.48) | ALDH1A1HSD17B10HPGDNPSR1KMT2A | |
| SCHEMBL9137938 | 0.74 | GAA (0.45) | ALDH1A1HPGDKMT2AGAAKDM4E | |
| SCHEMBL27869286 | 0.73 | ALDH1A1 (0.50) | ALDH1A1HSD17B10HPGDNPSR1KMT2A | |
| SCHEMBL27865912 | 0.73 | KMT2A (0.52) | ALDH1A1HSD17B10HPGDNPSR1KMT2A | |
| SCHEMBL31456338 | 0.73 | ALDH1A1 (0.67) | ALDH1A1HSD17B10HPGDNPSR1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109310671-B | Bruton's tyrosine kinase inhibitors | 淄博百极常生制药有限公司 | 2021-08-06 | — | — | CN | disclosed |